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“I used the xCELLigence DP system to study the effectiveness of CAR-T against target cancer cells. I was able to observe the effectiveness of cell therapy during the entire experiment with great accuracy. Both devices and software are easy and pleasant to use”

Dr Anna Bujak, Principal Research Scientist

Helix Immuno-Oncology, Warsaw, Poland

xCELLigence MP - Acea Biosciences

Higher throughput for xCELLigence cell based assay

The RTCA MP Station is located inside a tissue culture incubator and is capable of switching any one of the wells on any of six E-Plates to the RTCA Analyzer for impedance measurement.Each of the six E-Plate holders can be used independently under the RTCA Software. The RTCA Analyzer can automatically select wells for measurement and continuously transfer measured impedance data to the computer. Cell Index values, derived from the measured impedances, are continuously displayed on the Software user interface.

The RTCA MP Instrument is composed of four main components: 

  • RTCA Analyzer
  • RTCA MP Station
  • RTCA Control Unit
  • E-Plate 96

RTCA MP Instrument Highlights:

  • Higher assay throughput: Accommodates up to six E-Plates simultaneously
  • Flexibility: Independent operation of six E-Plates by up to six different users
  • Easy to use: Motorized mechanism for E-Plate engagement onto RTCA MP Station
  • Clear data presentation: 96-well graph shows individual Cell Index curves for all 96 wells

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https://www.aceabio.com/products/rtca-mp/

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Cancer Immunotherapy Applications of xCELLigence Real-Time Cell Analysis (RTCA) Systems xCELLigence cancer immunotherapy: NK cell-mediated cytolysis In vitro hypoxia studies using xCELLigence platform Real-time chemotaxis of macrophages Quantifying virus-mediated cytopathic effect with xCELLigence platform Introducing the xCELLigence Immunotherapy kit – B Cell killing assay Real-time monitoring of Human Skin-Derived Precursor (SKPs) cell differentiation Assessment of CAR T Cell killing capacity against solid tumors-Thursday, October 20, 2016, 5 pm CEST Cancer immunotherapy: Macrophage-mediated phagocytosis Monitoring in real time the formation and removal of biofilms from clinical related pathogens xCELLigence in personalized cancer medicine Investigating the hallmarks of cancer using xCELLigence system Monitoring the formation and removal of biofilms from clinically relevant pathogens in real-time Real-time determination of virus titers using cell electric impedance technology Label-free monitoring of T cell activation by the impedance-based system A novel high throughput assay for diagnosis by real-time monitoring of parasite motility Optimization of (CAR) T cell design guided by sensitive sssessment of B cell killing Cellular impedance measurement- novel method for in-vitro investigation of drug efficacy Cellular impedance measurement- response of OVCAR-3 cells to Cisplatin and hyperthermia ACEA webinar series: Using xCELLigence RTCA to study biofilms formation Kinase study of cytotoxicity voted paper of the year.
Katarzyna Nazarewicz

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Katarzyna

Nazarewicz

+48 797 701 027

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Instrument can be integrated with automated liquid handling platforms or a robotic plate handler from different vendors

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Located inside a tissue culture incubator, it is capable of switching any one of the wells on the E-Plate 96 to the RTCA Analyzer for impedance measurement

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