Discover

Back to filter

Related topics

Webinar: Multimodal tissue imaging and machine learning to advance precision medicine

RareCyte

May 17, 2023

Join us for this webinar to learn how the Orion spatial biology imaging platform was used to identify prognostic...

Cellenion’s solutions for isolation and sample preparation from Cells all the way to Spheroids

Cellenion

May 9, 2023

In this webinar, you will get an overview of Cellenion’s solutions for single cell and single 3D models applications:...

Recorded webinar: Anesthesia Considerations in Small Animal Imaging

Spectral Instruments Imaging

Mar 13, 2023

Anesthesia settings and operation of Optical Imaging Systems: methods, animal handling, safety and regulatory...

NanoCellect Webinar: Optimizing the Cell Line Development Process with Microfluidic Cell Sorting

NanoCellect

Mar 3, 2023

Single-cell selection and cloning are required for bioengineering workflows such as antibody production, cell therapy,...

Webinar: Spatial Biology and immunofluorescence to study human pancreata in in type 1 diabete

RareCyte

Feb 9, 2023

In this webinar, Dr. Quesada-Masachs from La Jolla Institute for Immunology reveals the image analysis pipeline that...

Advances in Leukemia research using shear flow and Bioflux system

Fluxion Biosciences

Feb 3, 2023

Leukemia is a rare cancer with many subtypes. The production of abnormal leukocytes create disruptions in the immune...

Webinar: Dose Reduction and Image Enhancement in Preclinical Mouse Imaging using Deep Learning

MOLECUBES

Jan 31, 2023

In this webinar, ir. Florence Muller (Ghent University - University of Pennsylvania) is presenting two recent studies...

Practical aspects of an imaging study: live in vivo scanning

MOLECUBES

Nov 11, 2022

In this webinar, MOLECUBES will present a live in vivo demonstration, showing the entire workflow from animal...

Advances in Leukemia research using shear flow and Bioflux system

Fluxion Biosciences

May 24, 2022

Leukemia is a rare cancer with many subtypes. The production of abnormal leukocytes create disruptions in the immune...

In-vivo webinar: a versatile use of SPECT/CT in the development of theranostic tracers

MOLECUBES

Mar 9, 2022

Combining (preclinical) imaging and targeted therapy, is the basis of theranostics. In this webinar, Dr. Florea will...

Show all topics (10)

Imaging of infection and tumors using labelled siderophores

Nov 15, 2017

Wednesday, December 6, 2017, 10 am CET, 5 pm CET.

Dr. Milos Petrik, Dr. Zbynek Novy, Institute of Molecular and Translational Medicine at Palacky University.

Siderophores are low-molecular weight, high affinity, iron-chelating ligands produced by many microorganisms as a means of acquiring iron. Iron is an essential nutrient in many cellular processes and therefore required for microbial proliferation and virulence. In iron-restricted conditions, some microorganisms produce large amounts of siderophores, which chelate free iron present in the environment and then carry it across the cell membrane, into the microorganism. Siderophores have demonstrated potential in the field of nuclear medical imaging; they can be labeled with radionuclides and used to detect microbial pathogens. Microbial cell specific transporters recognize and bind the radiolabelled siderophores, which are then taken up by the microbe. The pathogen can then be detected using nuclear imaging methods such as Positron Emission Tomography (PET). As well as infection imaging with siderophores, it is also possible to derivatize the siderophore molecule by conjugation of different targeting vectors such as peptides (eg. RGD and minigastrin) that have a high affinity for certain cell receptors and a near-infrared fluorophore enabling dual-modality imaging.
Join us at this webinar to learn more about these new experiences.

Register now

Webinar

Related technologies: PET, SPECT, CT

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

Related products

Albira combines PET, SPECT and CT imaging in a unique and extremely powerful way

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey