Automated microscopy and Spatial Proteomics
Automated microscopy and image analysis
Proteins
Protein interaction analysis
FIDA: Flow Induced Dispersion Analysis
FIDA uses first principles of physics and fluid mechanics to analyze the movement of particles in a fluid.
First, laminar flow is a smooth, non-turbulent flow of a fluid pushed through a capillary. In a laminar flow regime, the fluid moves in parallel streams.
Second, Taylor dispersion describes the behaviour of small particles in the flow. As the flow is laminar, the particles will not mix evenly, but instead experience a fluctuating motion. Such a motion results in a dispersion of the particles over time and space, as they diffuse and move along the flow.
FIDA technology takes advantage of these two principles by measuring fluorescence of particles in the laminar flow and analysing their dispersion over time, which allows for calculation of the hydrodynamic radius of a particle of interest.