Essen BioScience (part of Sartorius), is a team of engineers and biologists with deep expertise in cell-based assays. They invent, manufacture, supply and support cell-based assay instrumentation, reagents and protocols.
Discover
Related topics
Webinar: A simple Migration/Invasion workflow using IncuCyte Live-cell analysis system
Jan 27, 2021
Cell migration and invasion, or cell motility, play a role in many normal and...
Webinar : meet the Cytek's new cFluor reagents
Jan 25, 2021
Cytek Biosciences has already redefined what is possible in flow cytometry. The new Cytek...
Cytek full Spectrum flow Cytometry webinar: Part II – panel design and troubleshooting
Jan 11, 2021
In this session, we will continue to look at full spectrum flow cytometry and look at considerations for fluorescence...
NovoCyte Quanteon webinar: In-depth cell Proliferation through new advances in flow cytometry
Dec 11, 2018
Cell proliferation is one of the most fundamental biological processes in biology. Many of the traditional assays to...
Webinar: early detection of metabolic remodeling in pressure overload left ventricle Hypertrophy
Nov 28, 2018
Do you already heard the hypothesis that metabolic changes in the heart may precede and even trigger structural and...
Bioflux webinar: Blockade of CD62L inhibits CLL cell interaction with vascular endothelium
Nov 22, 2018
CD62L (L-selectin) is a key adhesion molecule that promotes cell tethering and rolling along the vascular endothelium...
Xcell Bio webinar: AVATAR system, to control cell state to get better cells, fast
Oct 30, 2018
Dr. Schneider will show examples of data from customers who have incorporated pressure along with oxygen to recreate...
Webinar Tuning Microenvironment to Control Cells for Improved Disease Modeling & Immunotherapy Work
Jul 16, 2018
The company producing Avatar, xCELL biosciences have organized a webinar about the tuning of microenvironment to...
How microCT can provide insight into dynamic disease processes webinar
Jun 19, 2018
Professor Vande Velde will describe how high-field MRI and low dose microCT complement each other; where microCT gives...
BioFlux webinar: Introducing new plates and capabilities of BioFlux microfluidic system
May 13, 2018
BioFlux biofilm assays can now be performed on the popular catheter material polydimethylsiloxane (PDMS). Silicone...
Jun 1, 2017
Tim Dale, Director of Biology, Europe, Essen BioScience
Alongside intense efforts to exploit T-cells as immunotherapies for cancer (e.g. checkpoint inhibitors, CAR-T, T-cell metabolism), researchers are increasingly considering other immune cell types for novel targets. One example is the enhancement of macrophage function via inhibitors of CD47 “don’t-eat-me” signalling proteins, enabling tumour cells to evade clearance by neighbouring phagocytes (Kim et al, 2012, Leukemia 26, 2538–2545). To identify new CD47 and phagocyte modulators, novel, direct and validated assays with throughput commensurate to drug discovery are required.
In this mini-webinar Tim Dale will:
-Illustrate how real-time live-cell analysis using pH-sensitive fluorescent probe-labelled target cells can be used to visualize and quantify phagocytosis.
-Share data on the pro-phagocytic effects of anti-CD47 antibodies.
-Demonstrate how other live-cell phenotypic assays (e.g. apoptosis, proliferation) are used to validate mechanisms of action.
Brand profile
Essen BioScience (part of Sartorius), is a team of engineers and biologists with deep expertise in cell-based assays. They invent, manufacture, supply and support cell-based assay instrumentation, reagents and protocols.
More info at:
www.essenbioscience.com/