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Thermal Shift Assay using SYPRO Orange to Detect Protein Melting Temperatures

The thermal shift assay is based on temperature-induced denaturation and can be monitored using SYPRO Orange. This fluorescence dye is a naturally quenched dye and interacts with the hydrophobic core of proteins which is exposed after denaturation.

May 2, 2023

Scientific paper
Application

Standardize tumor sample preparation and reduce background with Curiox laminar wash system

Laminar Wash technology offers a gentle alternative that can improve yield and data quality, particularly of rare cell types in samples containing low initial cell counts.

Aug 10, 2022

Application
Product news

Single-cell DNA Analysis of a Novel Acute Erythroid Leukemia CRISPR Induced Mouse Model

Assessment of precise genetic edits. Analysis of the clonal structure & co-mutations of AEL. Use of CRISPR and scDNA-seq for disease modeling.

May 9, 2021

Scientific paper
Application

Understanding the pathogenesis of FCD type II using qPCR

The quantitative polymerase chain reaction is the methodology to determine the essential and dominant role of cNEUROG2 gene in the pathogenesis of focal cortical dysplasia (FCD) type II.

Jul 18, 2018

Scientific paper
Application

Developing a 43 color panel on Cytek Aurora using Laminar Wash for sample prep

Successfully executing a 43 color panel is a technically demanding task. One that is made more difficult when there are confounding issues like non-specific binding and cell debris.

Aug 2, 2022

Application
Product news

SARS-CoV-2 detection workflow in wastewater - Analytik Jena and project in Japan

In 2020 Analytik Jena real-time PCR thermal cyclers of the qTOWER³ series even supported one of the first SARS-CoV-2 wastewater screenings in Japan.

May 8, 2021

Scientific paper
Application

First DLS paper: Sorghum genome assembled with nanopore sequencing and DLS

The new paper describes a chromosome-scale de novo assembly of the repeat-rich Sorghum bicolor Tx430 genome built using Oxford Nanopore sequence combined with Bionano’s Direct Label and Stain optical maps generated on Saphyr.

Jun 26, 2018

Application
Product news

Customer Story: Automation at DKMS LIFE SCIENCE LAB

How DKMS LIFE SCIENCE LAB is Supporting the Fight against Leukemia with New Processes and Automation

Nov 25, 2021

Product news

Adenovirus type B detection using the xxpress qPCR thermal cycler

The ultrafast xxpress qPCR thermal cycler through performing standard dilution series and multiplex qPCR experiments is compatible with Primerdesign genesig adenovirus type B kit designed for the in vitro quantification of AdVB genomes. 

Sep 17, 2018

Scientific paper
Application

Early fetal sex determination using micro-volume of maternal plasma

 A qPCR-based assay, SneakPeek Early Gender Test (Gateway Genomics) has been developed to determine fetal sex as early as 9 weeks gestation using a micro-volume of maternal plasma. 

Jun 16, 2018

Scientific paper
Application

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