3R Compliant drug development studies

Using an ultrasound instrument, animal throughput can be low and operators also need to be highly experienced simply to even find certain organs.

At the Center for Molecular Oncology at Barts Cancer Institute, Queen Mary University of London, researchers have been using preclinical imaging to look at the pharmacokinetics of radiopharmaceuticals, to perform anatomical studies, and to assess treatment responses in mice. The center is fully equipped for radiopharmaceutical development and houses a number of imaging instruments.

One of those instruments is the ICON 1 T MRI from Bruker. In a recent interview, team leader Dr. Jane Sosabowski, explained how the molecular imaging team have been using the ICON to investigate orthotopic pancreatic tumors in mice and described some of the advantages of using this over ultrasound.

Do you want to learn more? Read the whole article!