Optical tweezers, Confocal microscopy, STED nanoscopy, Acoustic force spectroscopy for single-molecule biophysics.
Automated microscopy and Spatial Proteomics
Automated microscopy and image analysis
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C-Trap and AFS systems mentioned in two review articles
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The articles state that biomolecular interactions are regulated by force, which drive many cellular processes. The C-Trap is recognized as a commercial system that implements high quality and user-friendly optical tweezers in a confocal microscope to reveal the dynamics of biomolecular interactions. Acoustic force spectroscopy is mentioned as an integrated system for high-throughput single-molecule experiments and data analysis to reveal heterogeneity within cellular processes and gather insights about multiple biomolecules in parallel.
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