The company provides a revolutionary cell culturing platform that replicates the physiological environment of native tissues to deliver reproducible and biologically relevant molecular analysis.
Discover
Related topics
Extensive assessment of Cytokine production on the NovoCyte Advanteon flow cytometer
Jan 13, 2023
Cytokines are small molecules essential for immune cell response to activation by pathogens, autoimmunity, or...
New installation of Cytek Aurora in Slovenia
Jan 11, 2023
2nd spectral flowcytometer Aurora from Cytek was installed at National Institute of Biology in Slovenia
Microfluidic cell sorter sample preparation for genomic assays
Dec 16, 2022
Single-cell RNA-Sequencing has led to many novel discoveries such as the detection of rare cell populations, microbial...
CellRad+ benchtop X-Ray irradiator
Dec 9, 2022
New CellRad+ benchtop irradiator for biological samples is coming with higher voltage and continue exposure for 180...
Dec 1, 2022
Cytek Cloud is the new digital ecosystem that supports full spectrum flow cytometry research from panel design to data...
See More, Sort More with Cytek Full Spectrum Systems
Nov 28, 2022
Still wondering whether to join the shift to full spectrum cytometry? Easily transfer assays from your Cytek Northern...
Demonstrate the value of RareCyte Orion system via web-based Minerva viewer
Nov 25, 2022
The HTA CRC Atlas X dataset contains images and other data being used for construction of an atlas of human colorectal...
RareCyte Orion system advances Multi-modal digital pathology for colorectal cancer diagnosis
Oct 19, 2022
Precision medicine is critically dependent on better methods for diagnosing and staging disease and predicting drug...
Introducing MARS system : revolutionary solution for your workflow of cell separation and enrichment
Oct 7, 2022
The MARS family of instruments provides a breakthrough solution to complete the workflow of cell separation and...
Understand the Cancer Ecosystem based on single cells analysis
Sep 22, 2022
Mission Bio is a life sciences company that accelerates discoveries and cures for a wide range of diseases by equipping...
Oct 17, 2017
The Avatar system from Xcell Biosciences was originally designed to maintain and propagate human stem cells under culturing conditions that replicate the stem cell niche. The system was modified to cultivate a variety of primary human tumor cells, including CTCs, by replicating conditions found within the tumor microenvironment. The Avatar system incorporates a unique bioreactor that regulates settings for oxygen and atmospheric pressure levels, in addition to the usual temperature and carbon dioxide controls. Complementing the novel bioreactor are serum-free, chemically defined culture media composed of recombinant human growth factors, and a CTC-capture substrate composedof a collagen-based hydrogel.
The workflow was developed in response to mounting evidence that hypoxia and pressure are influential traits in the cellular microenvironment that contribute to the maintenance and propagation of tumorcells. When complemented with an optimal cocktail of growth factors and a collagen-rich substrate found within tumor tissues, tumor cells can be maintained and propagated ex vivo, at rates similar to those observed in the body. Other studies investigatingcell morphology as well as gene and protein expression profiles have shown that cells cultured in the Avatar system more faithfully reflect in vivo biology than cells grown in traditional CO2 incubators supplemented with animal serum-based culture media.
Brand profile
The company provides a revolutionary cell culturing platform that replicates the physiological environment of native tissues to deliver reproducible and biologically relevant molecular analysis.
More info at:
www.xcellbio.com