Mauna Kea Technologies manufactures Cellvizio Lab, confocal probe based imaging system, providing cellular-level images with minimal invasiveness for longitudinal studies.
Discover
Back to filter
Show all topics (10)
Related topics
Curiox webinar - how to retain more cells for Single Cell Sequencing and proteogenomics ?
Feb 15, 2021
Curiox Laminar Wash technology has been added as part of the official BioLegend TotalSeq...
Cytek Aurora in Action : how to easily resolve highly overlapping dyes ?
Feb 2, 2021
Learn from Jeff Nelson, a manager of a cytometry shared resource laboratory, about the...
Webinar: A simple Migration/Invasion workflow using IncuCyte Live-cell analysis system
Jan 27, 2021
Cell migration and invasion, or cell motility, play a role in many normal and...
Webinar : meet the Cytek's new cFluor reagents
Jan 25, 2021
Cytek Biosciences has already redefined what is possible in flow cytometry. The new Cytek...
Introducing Cytek cFluor, 14 Colors Immunoprofiling Kit
Jan 19, 2021
Cytek cFluor Immunoprofiling Kit allows for the identification of helper T cells,...
Cytek full Spectrum flow Cytometry webinar: Part II – panel design and troubleshooting
Jan 11, 2021
In this session, we will continue to look at full spectrum flow cytometry and look at considerations for fluorescence...
IncuCyte for in-vitro analysis of SARS-CoV-2 vaccine candidate
Jan 4, 2021
Watch this video to learn how researcher at Humane Genomics are utilizing the Incucyte...
Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice
Dec 29, 2020
Radio-active sources have been used routinely for the preconditioning in humanized mouse...
Advances in Leukemia research using shear flow and Bioflux system
Dec 10, 2020
Leukemia is a rare cancer with many subtypes. The production of abnormal leukocytes...
Do you have our CellRad benchtop irradiator? It’s the only one on the market!
Dec 9, 2020
The CellRad is a smaller, simpler, safer, and more cost effective alternative to...
De novo design of a biologically active amyloid
Feb 5, 2018
Most human proteins possess amyloidogenic segments, but only about 30 are associated with amyloid-associated pathologies, and it remains unclear what determines amyloid toxicity. Gallardo et al. designed vascin, a synthetic amyloid peptide, based on an amyloidogenic fragment of vascular endothelial growth factor receptor 2 (VEGFR2), a protein that is not associated to amyloidosis. Vascin recapitulates key biophysical and biochemical characteristics of natural amyloids, penetrates cells, and seeds the aggregation of VEGFR2 through direct interaction. They found that amyloid toxicity is observed only in cells that both express VEGFR2 and are dependent on VEGFR2 activity for survival. Thus, amyloid toxicity here appears to be both protein-specific and conditional—determined by VEGFR2 loss of function in a biological context in which target protein function is essential.
Brand profile
