Mauna Kea Technologies manufactures Cellvizio Lab, confocal probe based imaging system, providing cellular-level images with minimal invasiveness for longitudinal studies.
Discover
Back to filter
Show all topics (10)
Related topics
Early immune response in mice immunized with inactivated vaccine against SARS-CoV-2
Nov 23, 2020
The development of a vaccine against COVID-19 is a hot topic for many research laboratories all over the world. Our aim...
CS-FNX Hitachi Koki, discover the state-of-art ultracentrifuges series
Nov 19, 2020
Hitachi Koki, as a world leading producer of centrifuges offers general purpose floor standing and table top...
Curiox webinar - how to retain more cells for Single Cell Sequencing and proteogenomics ?
Nov 19, 2020
Do you think that centrifuging cells at 500 x g is not going to cause issues? Moreover, sample prep involving...
Discover the new NovoCyte Penteon - when exceptional performance meets simplicity
Nov 18, 2020
The NovoCyte Penteon flow cytometer builds on its successful predecessor, the NovoCyte. You now have the flexibility to...
Cellular stress induces erythrocyte assembly and promotes microangiopathy
Dec 19, 2018
Microangiopathy with subsequent organ damage represents a major complication in several diseases. The mechanisms...
The need for ultra high field magnetic resonance imaging
Dec 17, 2018
MRI is a noninvasive imaging technology that is known for its superior soft tissue contrast and ability to provide...
NovoCyte Quanteon webinar: In-depth cell Proliferation through new advances in flow cytometry
Dec 11, 2018
Cell proliferation is one of the most fundamental biological processes in biology. Many of the traditional assays to...
Webinar: early detection of metabolic remodeling in pressure overload left ventricle Hypertrophy
Nov 28, 2018
Do you already heard the hypothesis that metabolic changes in the heart may precede and even trigger structural and...
IncuCyte neuronal activity assay
Nov 13, 2018
The generation and maturation of neuronal networks are necessary characteristics of neurogenesis, providing...
The most advanced software for preclinical imaging research
Nov 7, 2018
Modern imaging laboratories hosting PET/MR instruments profit from the fully integrated common imaging platform...
De novo design of a biologically active amyloid
Feb 5, 2018
Most human proteins possess amyloidogenic segments, but only about 30 are associated with amyloid-associated pathologies, and it remains unclear what determines amyloid toxicity. Gallardo et al. designed vascin, a synthetic amyloid peptide, based on an amyloidogenic fragment of vascular endothelial growth factor receptor 2 (VEGFR2), a protein that is not associated to amyloidosis. Vascin recapitulates key biophysical and biochemical characteristics of natural amyloids, penetrates cells, and seeds the aggregation of VEGFR2 through direct interaction. They found that amyloid toxicity is observed only in cells that both express VEGFR2 and are dependent on VEGFR2 activity for survival. Thus, amyloid toxicity here appears to be both protein-specific and conditional—determined by VEGFR2 loss of function in a biological context in which target protein function is essential.
Related technologies: Probe based confocal microscopy
Brand profile
