Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.
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Fluorescent reagents for in vivo optical imaging
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There have been two primary developments in the evolution of in vivo fluorescent reagents during this time (1) red-shifted fluorescent proteins (e.g. tdTomato) and NIR dyes (e.g. Cy7), which are more commonly used for in vivo imaging applications and (2) the range of validated targeted probes, which has expanded significantly.
Bruker Optical/X-ray imaging systems are equipped standard with full multispectral (Yudina et al., 2016) fluorescence VISNIR imaging capability, compatible with most custom and commercial reporters.
Also, Bruker Optical/X-ray imaging systems have been employed with a range of fluorescent reporters including but not limited to YFP, eGFP, mCherry, and many others.
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