Discover

Back to filter

Related topics

WEBINAR: Recent Advancements In Neurodegenerative Biomarkers

Quanterix

Sep 6, 2021

Recent Advancements in Neurodegenerative Biomarkers: Progress Towards a Diagnostic Blood Test for Alzheimer’s Disease

How to Improve Your Viral Nucleic Acid Extraction Processes

Analytik Jena

Sep 6, 2021

High-Throughput Extraction with CyBio FeliX

Introducing New Aura 4.0 software

Spectral Instruments Imaging

Aug 31, 2021

With new features for both acquisition & analysis Aura Software enables you to capture and analyze your data quickly,...

Comparison of gamma and x-ray irradiation results

Precision X-Ray

Aug 12, 2021

Biological effects of Cs-137 and X-ray irradiators are comparable with regards to...

Hypoxia further exacerbates myopathy in broilers via alteration of satellite cell fate

COY laboratory products

Aug 2, 2021

Woody breast (WB) condition has created a variety of challenges for the global poultry...

Top 10 Pharma companies have chosen CYTEK for their flow cytometry facility

Cytek Biosciences

Jul 15, 2021

6 of Top 10 Pharma Companies (Based on total group revenues) have chosen CYTEK - full...

Webinar recording: Autofluorescence management - the power of Spectral Flow Cytometry

Cytek Biosciences

Jul 15, 2021

One of the key advantages of spectral flow cytometry is its ability to extract sample...

Webinar recording: Super-Resolution imaging of Chromatin organization in health and disease

ONI

Jul 9, 2021

Understanding how cells organize the array of components within their membranous confines can not only provide insight...

Show all topics (10)

High quality Bioluminescence and X-Ray analysis in lung squamous cell carcinoma

Jul 21, 2021

Engineered with superior optics and industry leading technology, Spectral Instruments Imaging provides unrivaled sensitivity for bioluminescence, fluorescence and X-ray in vivo imaging. Intelligently designed around the needs of animal scientists, all Spectral Instrument Imaging systems include a robust build, patented LED illumination source, custom filter options, -90°C cooled camera, and absolute calibration.
Bioluminescent signal intensity is a function of luciferase substrate kinetics. These kinetics are generally tissue dependent and can also vary over time, as a result of disease-related pathologies and physiologies. In BLI studies, one should identify and compare peak bioluminescent values over the time course of the study. This is best done by establishing bioluminescent kinetic curves at each imaging time point. Such curves are made by injecting, anesthetizing and then imaging animals over a span of several time points post-luciferin injection. Typically, imaging starts at 5 minutes post injection, is repeated every 5-10 minutes, and completed once signal intensities start to decline.


Read more about Bioluminescence (BLI) and X-Ray in vivo imaging applications in case of lung squamous cell carcinoma (LUSC), in a study published in Nature in February 2021.

Scientific paper
Application

Get more info

Katarzyna Nazarewicz

Country manager

Katarzyna

Nazarewicz

+48 797 701 027

Send Message

Brand profile

Spectral Instruments Imaging

Spectral Instruments Imaging manufactures instruments for preclinical optical (bioluminescent, fluorescent) and X-ray imaging.

Related products

The Ami HT and Ami HTX (includes X-Ray imaging) optical imaging systems establish a new, high throughput benchmark for in vivo imaging suitable for specialist researchers and small teams.

show detail

The Lago and X‐Ray capable Lago X optical imaging systems provide a powerful and flexible in-vivo imaging capability suitable for imaging cores, specialist researchers and small teams, delivering an unmatched 10 mouse capacity across BLI, FLI and X‐Ray.

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey