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Cytek webinar: Imaging Flow Cytometry for Chromosomal Assessment in Hematological Malignancies

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In this webinar, we will describe a new innovative approach we developed that resolves these limitations. The method...

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Disha Moholkar of University of Louisville's Gupta Lab
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Emulate in vivo conditions – introduce shear flow to your experiments with BioFlux system

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Blood biomarkers showed values for predicting future cohnitive impairment. Evidence from the community-based cohort was...

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High-throughput observation of molecular motor activity & dynamics

Feb 21, 2018

The cytoskeleton and its many molecular motors are major players in a variety of cellular functions. The interconnected networks of cytoskeletal filaments act as tracks directing molecular motor transport and provide structural support and organization to cells. With optical tweezers, we are capable of resolving sub-nanometer displacements and applying pico-Newton forces on single proteins. This force spectroscopy approach has proven extremely useful in elucidating the mechanics and kinetics of molecular motors involved in intracellular transport. 

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LUMICKS

Optical tweezers, Confocal microscopy, STED nanoscopy, Acoustic force spectroscopy for single-molecule biophysics. 

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Acoustic Force Spectroscopy is a single-molecule, lab-on-a-chip technology in which acoustic waves are used to exert forces on thousands of biomolecules.

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