Discover

Back to filter

Related topics

EV's and Nanoparticles in "Full Spectrum View" with the new Cytek ESP module

Cytek Biosciences

Jul 19, 2024

Cytek’s Enhanced Small Particle (ESP) Detection Option expands the capability of your Cytek Aurora or Cytek Northern...

Study finds that automated liquid-handling operations are more robust, resilient, and efficient!

Analytik Jena

Jul 18, 2024

Liquid handling devices (LHD) improve lab efficiency and accuracy. They automate liquid transfers, increase experiment...

Scaling Whole-Genome Sequencing to >50,000 single cells using cellenONE

Cellenion

Jul 16, 2024

cellenONE technology enabled the creation of tens of thousands of high-quality single-cell genomes, paving the way for...

Theranostics: From Mice to Men and Back

MOLECUBES

Jun 25, 2024

Recorded webinar
Presenters: Prof. Dr. Ken Herrmann and Prof. Dr. Katharina Lückerath – Moderator: Hannah Notebaert

Orion 2024 AACR poster: 17-plex single-step stain and imaging of cell Lung Carcinoma

RareCyte

Jun 21, 2024

RareCyte Orion is a benchtop, high resolution, whole slide multimodal imaging instrument. A combination of quantitative...

New release now available: Cytek Amnis AI v3.0 Software

Cytek Biosciences

Jun 17, 2024

The new Cytek Amnis AI v3.0 image analysis software features an integrated transfer learning algorithm, an option to...

Automated Purification of Viral DNA and RNA from Biological Samples usingZymo Research Quick-DNA/RNA

Analytik Jena

Jun 14, 2024

The Quick DNA/RNA Viral MagBead Kit from Zymo has been automated with the Cybio FeliX pipetting robot from Analytik...

DNA Amplicon Library Preparation for Illumina® Sequencing

Analytik Jena

Jun 12, 2024

The precision of temperature control, efficient heating and cooling rates, and excellent temperature homogeneity across...

Cytek webinar: Imaging Flow Cytometry for Chromosomal Assessment in Hematological Malignancies

Cytek Biosciences

Jun 7, 2024

In this webinar, we will describe a new innovative approach we developed that resolves these limitations. The method...

X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization

Precision X-Ray

Jun 5, 2024

Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...

Show all topics (10)

Hybrid X-Ray/Optical imaging of organic fluorophores

Sep 19, 2016

Traditional in vivo fluorescent imaging commonly employs fluorescent protein reporters, including site-directed and enzyme-activatable conjugates. Red-shifted and NIR (700 – 900 nm) fluorophore reporters are now considered mainstream for in vivo imaging applications, due to the relatively low levels of light scatter and autofluorescence when used in living specimens. Recently, there have been reports of in vivo imaging with luminescent or fluorescent probes that are X-Ray activated (Carpenter et al., 2010; Osakada et al., 2013; 2014). This hybrid X-Ray/optical approach has the potential to offer the combined deeper imaging associated with X-Ray and functional detection associated with targeted optical agents. Reports that detail hybrid X-Ray/optical imaging with organic fluorophores are exceedingly rare. Here, we provide a preliminary, in vitro evaluation of selected, commercial organic fluorophores including anthracene, carbocyanine (Cy7), Rhodamine B (Rho), Carboxyfluorescein CF), and Squaraine Rotatxane (SR) as agents for X-Ray induced fluorescence (XRIF) imaging, using the Bruker In-Vivo Xtreme imaging system.

Read more

Scientific paper
Technical breakthrough
Application

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey