Discover

Back to filter

Related topics

Extensive assessment of Cytokine production on the NovoCyte Advanteon flow cytometer

Agilent technologies

Jan 13, 2023

Cytokines are small molecules essential for immune cell response to activation by pathogens, autoimmunity, or...

Microfluidic cell sorter sample preparation for genomic assays

NanoCellect

Dec 16, 2022

Single-cell RNA-Sequencing has led to many novel discoveries such as the detection of rare cell populations, microbial...

Demonstrate the value of RareCyte Orion system via web-based Minerva viewer

RareCyte

Nov 25, 2022

The HTA CRC Atlas X dataset contains images and other data being used for construction of an atlas of human colorectal...

RareCyte Orion system advances Multi-modal digital pathology for colorectal cancer diagnosis

RareCyte

Oct 19, 2022

Precision medicine is critically dependent on better methods for diagnosing and staging disease and predicting drug...

Automating DNA Extraction for High-Throughput Bacterial Plasmid Purification with CyBi®-SELMA

Analytik Jena

Sep 19, 2022

The Need to Increase Plasmid Isolation Throughput, Challenges with Scaling up Plasmid DNA Extraction, Automating the...

Transcriptome-Informed Approach to Drug Discovery

HTG Molecular Diagnostics

Jul 12, 2022

The HTG EdgeSeq system is a powerful molecular profiling tool for biopharmaceutical companies, academic research...

Semi-automated genomic DNA extractionfrom Plant with CyBi®-SELMA

Analytik Jena

Jul 12, 2022

Plant genomic DNA extraction with CyBio SELMA, Semi-Automated Pipette with minimal benchtop footprint

Outstanding post-sort sample recovery on the WOLF Cell Sorter

NanoCellect

Jun 14, 2022

The new WOLF G2 instrument has significantly expanded the capabilities of gentle benchtop microfluidic cell sorting...

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters

MOLECUBES

Jun 3, 2022

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine...

Quantitative 3D Optical Imaging for Lago

Spectral Instruments Imaging

Feb 21, 2022

Spectral Instrument Imaging just announced a new, strategic partnership with InVivo Analytics, which enables...

Show all topics (10)

Hypoxia activates constitutive Luciferase reporter constructs

Jul 13, 2017

Studies in our laboratory sought to examine the hypoxic regulation of HIF activity in placental trophoblast cells, through the use of dual-reporter luciferase assays. Our study demonstrates that hypoxic conditions cause a significant increase in the level of constitutive luciferase reporter activity. We also show that this induction is not a cell-type or species-specific phenomenon and provides an alternative method for normalizing transfection efficiency in luciferase assays under hypoxic conditions. Our results suggest that in studies dealing with hypoxic conditions, caution should be used when interpreting measurements of transcriptional activity by traditional dual-reporter assays.

Read more

 

Scientific paper

Brand profile

COY laboratory products

Coy Labs produces Glove Boxes, Anaerobic Chambers, and controlled atmosphere glove boxes.

Related products

The flexible nature of the unit allows for the user to reach deeper and higher into the unit

show detail

Gloveless anaerobic chambers offer the operator a convenient glove-free ability to handle and inspect samples under low oxygen (0-5 ppm) conditions

show detail

InVitro glove boxes – incubation, culture maintenance and analysis in the same environment

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey