Coy Labs produces Glove Boxes, Anaerobic Chambers, and controlled atmosphere glove boxes.
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Extensive assessment of Cytokine production on the NovoCyte Advanteon flow cytometer
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Demonstrate the value of RareCyte Orion system via web-based Minerva viewer
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RareCyte Orion system advances Multi-modal digital pathology for colorectal cancer diagnosis
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Automating DNA Extraction for High-Throughput Bacterial Plasmid Purification with CyBi®-SELMA
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The Need to Increase Plasmid Isolation Throughput, Challenges with Scaling up Plasmid DNA Extraction, Automating the...
Transcriptome-Informed Approach to Drug Discovery
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The HTG EdgeSeq system is a powerful molecular profiling tool for biopharmaceutical companies, academic research...
Semi-automated genomic DNA extractionfrom Plant with CyBi®-SELMA
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Plant genomic DNA extraction with CyBio SELMA, Semi-Automated Pipette with minimal benchtop footprint
Outstanding post-sort sample recovery on the WOLF Cell Sorter
Jun 14, 2022
The new WOLF G2 instrument has significantly expanded the capabilities of gentle benchtop microfluidic cell sorting...
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters
Jun 3, 2022
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine...
Quantitative 3D Optical Imaging for Lago
Feb 21, 2022
Spectral Instrument Imaging just announced a new, strategic partnership with InVivo Analytics, which enables...
Hypoxia activates constitutive Luciferase reporter constructs
Jul 13, 2017
Studies in our laboratory sought to examine the hypoxic regulation of HIF activity in placental trophoblast cells, through the use of dual-reporter luciferase assays. Our study demonstrates that hypoxic conditions cause a significant increase in the level of constitutive luciferase reporter activity. We also show that this induction is not a cell-type or species-specific phenomenon and provides an alternative method for normalizing transfection efficiency in luciferase assays under hypoxic conditions. Our results suggest that in studies dealing with hypoxic conditions, caution should be used when interpreting measurements of transcriptional activity by traditional dual-reporter assays.
Related technologies: Hypoxia and O2 controlled environment isolators | Anaerobic boxes
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