Coy Labs produces Glove Boxes, Anaerobic Chambers, and controlled atmosphere glove boxes.
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Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters
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Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine...
Quantitative 3D Optical Imaging for Lago
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Extensive assessment of Cytokine production on the NovoCyte Penteon flow cytometer
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How to Improve Your Viral Nucleic Acid Extraction Processes
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Comparison of gamma and x-ray irradiation results
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Hypoxia further exacerbates myopathy in broilers via alteration of satellite cell fate
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Woody breast (WB) condition has created a variety of challenges for the global poultry...
Hypoxia activates constitutive Luciferase reporter constructs
Jul 13, 2017
Studies in our laboratory sought to examine the hypoxic regulation of HIF activity in placental trophoblast cells, through the use of dual-reporter luciferase assays. Our study demonstrates that hypoxic conditions cause a significant increase in the level of constitutive luciferase reporter activity. We also show that this induction is not a cell-type or species-specific phenomenon and provides an alternative method for normalizing transfection efficiency in luciferase assays under hypoxic conditions. Our results suggest that in studies dealing with hypoxic conditions, caution should be used when interpreting measurements of transcriptional activity by traditional dual-reporter assays.
Related technologies: Hypoxia and O2 controlled environment isolators | Anaerobic boxes
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