Discover

Back to filter

Related topics

Cellular stress induces erythrocyte assembly and promotes microangiopathy

Fluxion Biosciences

Dec 19, 2018

Microangiopathy with subsequent organ damage represents a major complication in several diseases. The mechanisms...

The need for ultra high field magnetic resonance imaging

Bruker Biospin

Dec 17, 2018

MRI  is a noninvasive imaging technology that is known for its superior soft tissue contrast and ability to provide...

The most advanced software for preclinical imaging research

Bruker Biospin

Nov 7, 2018

Modern imaging laboratories hosting PET/MR instruments profit from the fully integrated common imaging platform...

Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs

Fluxion Biosciences

Oct 12, 2018

Drug delivery by nanocarriers (NCs) has long been stymied by dominant liver uptake and limited target organ deposition,...

Adenovirus type B detection using the xxpress qPCR thermal cycler

BJS Biotechnologies

Sep 17, 2018

The ultrafast xxpress qPCR thermal cycler through performing standard dilution series and multiplex qPCR experiments is...

Diagnosis of Acute Cellular Rejection Using Probe-Based Confocal Laser Endomicroscopy in Lung

Mauna Kea Technologies

Sep 3, 2018

Mauna Kea Technologies announced the publication of a prospective multicenter study that demonstrates the potential of...

Functional Imaging

Bruker Biospin

Aug 9, 2018

We bring you the latest KOL interview on the Albira Si PET/SPECT/CT from Prof. John Prior, CHUV Lausanne. He describes...

Differentation displacement in acute myeloid leukemia through enhancer activation

Acea Biosciences

Aug 7, 2018

Blast cell differentation is inhibitited by pharmacological targeting of lysine specific demethylase 1 (LSD1). In this...

Dynamic PET imaging and special focus in cardiac kinetic analysis

Bruker Biospin

Aug 1, 2018

Micro-computed tomography, or micro-CT, is being employed by a rapidly increasing number of laboratories for bone...

Novel insights on the mechanical properties of IFs using LUMICKS’ technology

LUMICKS

Jul 30, 2018

The journal Science Advances has recently published the paper ‘Viscoelastic properties of vimentin originate from...

Show all topics (10)

Hypoxia activates constitutive Luciferase reporter constructs

Jul 13, 2017

Studies in our laboratory sought to examine the hypoxic regulation of HIF activity in placental trophoblast cells, through the use of dual-reporter luciferase assays. Our study demonstrates that hypoxic conditions cause a significant increase in the level of constitutive luciferase reporter activity. We also show that this induction is not a cell-type or species-specific phenomenon and provides an alternative method for normalizing transfection efficiency in luciferase assays under hypoxic conditions. Our results suggest that in studies dealing with hypoxic conditions, caution should be used when interpreting measurements of transcriptional activity by traditional dual-reporter assays.

Read more

 

Scientific paper

Brand profile

COY laboratory products

Coy Labs produces Glove Boxes, Anaerobic Chambers, and controlled atmosphere glove boxes.

Related products

The flexible nature of the unit allows for the user to reach deeper and higher into the unit

show detail

Gloveless anaerobic chambers offer the operator a convenient glove-free ability to handle and inspect samples under low oxygen (0-5 ppm) conditions

show detail

InVitro glove boxes – incubation, culture maintenance and analysis in the same environment

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey