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Recent publication of in-vivo two-photon intravital imaging study targeting mouse kidney

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In vivo longitudinal 920 nm two-photon intravital kidney imaging of a dynamic 2,8-DHA crystal
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Mantis ROI calculator

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Using full spectrum flow cytometry, Cytek systems ( RUO and CE-IVD) detect the entire fluorochrome emission, allowing...

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The thermal shift assay is based on temperature-induced denaturation and can be monitored using SYPRO Orange. This...

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InAlyzer is body densitometry instrument for lab animals, equipped with 2 X-Ray sources and able to provide valuable...

Flash news - did you know, that you can use Singulator S100 also for plant research?

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Demonstrate the value of RareCyte Orion system via web-based Minerva viewer

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The HTA CRC Atlas X dataset contains images and other data being used for construction of an atlas of human colorectal...

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Hypoxia activates constitutive Luciferase reporter constructs

Jul 13, 2017

Studies in our laboratory sought to examine the hypoxic regulation of HIF activity in placental trophoblast cells, through the use of dual-reporter luciferase assays. Our study demonstrates that hypoxic conditions cause a significant increase in the level of constitutive luciferase reporter activity. We also show that this induction is not a cell-type or species-specific phenomenon and provides an alternative method for normalizing transfection efficiency in luciferase assays under hypoxic conditions. Our results suggest that in studies dealing with hypoxic conditions, caution should be used when interpreting measurements of transcriptional activity by traditional dual-reporter assays.

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COY laboratory products

Coy Labs produces Glove Boxes, Anaerobic Chambers, and controlled atmosphere glove boxes.

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The flexible nature of the unit allows for the user to reach deeper and higher into the unit

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Gloveless anaerobic chambers offer the operator a convenient glove-free ability to handle and inspect samples under low oxygen (0-5 ppm) conditions

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InVitro glove boxes – incubation, culture maintenance and analysis in the same environment

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