Coy Labs produces Glove Boxes, Anaerobic Chambers, and controlled atmosphere glove boxes.
Automated microscopy and Spatial Proteomics
Automated microscopy and image analysis
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The chicken chorioallantoic membrane as a low-cost, high-throughput model for cancer imaging
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Here, we assessed the chicken chorioallantoic membrane (CAM) as an alternative to mice for preclinical cancer imaging...
A microthrombus-driven fixed-point cleaved nanosystem for preventing post-thrombolysis recurrence
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A 19-color single-tube Full Spectrum Flow Cytometry for the detection of Acute Myeloid Leukemia
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This recent publication in Cytometry Part A describes the development and comprehensive workflow of a single-tube,...
18F-labeled somatostatin analogs for somatostatin receptors (SSTRs) targeted PET imaging of NETs
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A novel 18F-radiolabeled somatostatin analogue, [Al18F]NODA-MPAA-HTA, was synthesized and evaluated for positron...
Discover Yokogawa CellVoyager CQ1: Benchtop High-Content Analysis System
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Unlike flow cytometers, the CellVoyager CQ1 confocal quantitative image cytometer does not require pretreatment such as...
Visualization of Tumor-Related Blood Vessels in Small Animals by Photoacoustic 3D Imaging System
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In Vivo Label-Free Observation of Tumor-Related Blood Vessels in Small Animals Using a Newly Designed Photoacoustic 3D...
Therapeutic effects of mesenchymal stem cells in myocardial infarction
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Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem...
Evaluation with BLI of synthetic immune checkpoint engagers in allogenic mice
Jan 17, 2024
Synthetic immune checkpoint engagers protect HLA-deficient iPSCs and derivatives from innate immune cell cytotoxicity
Application of focal X-ray irradiation in canaries
Jan 15, 2024
Effects of the depletion of neural progenitors by focal X-ray irradiation on song production and perception in canaries
Hypoxia activates constitutive Luciferase reporter constructs
Jul 13, 2017
Studies in our laboratory sought to examine the hypoxic regulation of HIF activity in placental trophoblast cells, through the use of dual-reporter luciferase assays. Our study demonstrates that hypoxic conditions cause a significant increase in the level of constitutive luciferase reporter activity. We also show that this induction is not a cell-type or species-specific phenomenon and provides an alternative method for normalizing transfection efficiency in luciferase assays under hypoxic conditions. Our results suggest that in studies dealing with hypoxic conditions, caution should be used when interpreting measurements of transcriptional activity by traditional dual-reporter assays.
Related technologies: Hypoxia and O2 controlled environment isolators | Anaerobic boxes
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