Coy Labs produces Glove Boxes, Anaerobic Chambers, and controlled atmosphere glove boxes.
Automated microscopy and Spatial Proteomics
Automated microscopy and image analysis
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Factors Affecting Petri Dish Condensation in Tissue Culture (CU) Chambers
Nov 29, 2023
In this report, we will investigate the effects of infrared lighting, light intensity, stacking, as well as constant...
Visualization of spatial distribution of hemoglobin with various oxygen saturations in small animals
Nov 28, 2023
With the aid of our uniquely developed device and analysis software, our primary objective is to map the spatial...
A fluorescent reporter system for anaerobic thermophiles
Nov 27, 2023
Anaerobic microorganisms are key effectors for the sustainable production of biofuels and biochemicals, as they...
Vizgen webinar: spatial relationships in Developmental Biology
Nov 21, 2023
MERFISH integrates spatial transcriptomics technology with high resolution spatial imaging, In this webinar we will...
SIMOA-based analysis of plasma NFL levels in MCI and AD patients
Nov 3, 2023
The single-molecule array assay (SIMOA)-based detection of neurofilament light (NFL) chain could be useful in...
Single cell genotypic and phenotypic analysis of residual disease in acute myeloid leukemia
Nov 1, 2023
Measurable residual disease (MRD), defined as the population of cancer cells which persists following therapy, serves...
Validation of an orthotopic non-small cell lung cancer mouse model to use in radiotherapy studies
Oct 30, 2023
The use of pre-clinical orthotopic mouse models is essential for the development of novel therapies targeting solid...
Atypical Teratoid Rhabdoid Tumours Are Susceptible to Panobinostat-Mediated Differentiation Therapy
Oct 20, 2023
To assess tumour growth, mice were imaged using the AMI-HTX bioluminescent imaging system (Spectral Instruments...
IVIM in vivo platform to study efficacy of adoptive and anti-PD- 1- based immunotherapy
Oct 18, 2023
Low molecular weight heparin synergistically enhances the efficacy of adoptive and anti-PD-1-
based immunotherapy...
Orion spatial biology platform provides new insight for clinical trial designs
Oct 5, 2023
A breakthrough study just published by Dr. Pashtoon Kasi and colleagues (Weill Cornell Medicine) shares the exciting...
Hypoxia activates constitutive Luciferase reporter constructs
Jul 13, 2017
Studies in our laboratory sought to examine the hypoxic regulation of HIF activity in placental trophoblast cells, through the use of dual-reporter luciferase assays. Our study demonstrates that hypoxic conditions cause a significant increase in the level of constitutive luciferase reporter activity. We also show that this induction is not a cell-type or species-specific phenomenon and provides an alternative method for normalizing transfection efficiency in luciferase assays under hypoxic conditions. Our results suggest that in studies dealing with hypoxic conditions, caution should be used when interpreting measurements of transcriptional activity by traditional dual-reporter assays.
Related technologies: Hypoxia and O2 controlled environment isolators | Anaerobic boxes
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