Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.
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Leukemia is a rare cancer with many subtypes. The production of abnormal leukocytes create disruptions in the immune...
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Microfluidic cell sorter sample preparation for genomic assays
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Single-cell RNA-Sequencing has led to many novel discoveries such as the detection of rare cell populations, microbial...
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The HTA CRC Atlas X dataset contains images and other data being used for construction of an atlas of human colorectal...
Practical aspects of an imaging study: live in vivo scanning
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In-ovo magnetic resonance imaging
Jan 23, 2018
In-ovo MRI is a preclinical imaging technique in oncology research that involves the study of chicken egg embryos and a structure called the chorioallantoic membrane (CAM). The CAM is a highly vascularized and specialized tissue that performs various functions during embryonic development. The CAM model is a simple, low-cost and highly effective tool in the study of tumor angiogenesis, tumor growth, metastasis and cancer treatment; processes that can all be non-invasively monitored using MRI.
In ovo MRI provides an efficient testing technique to determine promising compounds and therefore minimizes the number of necessary animal experiments. Furthermore, eggs are readily available and often cheap in comparison to research animals. Since the embryonic phase is immunodeficient, cells from different tissues and species can easily be transplanted and studied, including human cell lines.
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