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High-frequency Ultrasound System For Preclinical Imaging

S-Sharp

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The Prospect T1 is an innovative high-frequency ultrasound system designed specifically for in vivo preclinical imaging...

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Vizgen

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Mounting evidence implicated the classical complement pathway (CP) in normal brain development, and the pathogenesis of...

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Quanterix

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Blood biomarkers showed values for predicting future cohnitive impairment. Evidence from the community-based cohort was...

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Precision X-Ray

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Here, we assessed the chicken chorioallantoic membrane (CAM) as an alternative to mice for preclinical cancer imaging...

A microthrombus-driven fixed-point cleaved nanosystem for preventing post-thrombolysis recurrence

IVIM Technology

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A thrombin-responsive and fixed-point cleaved Fu@pep-CLipo was developed for highly efficient and precise thrombolysis...

Multiplexed tissue imaging using the Orion platform to reveal the Spatial Biology of Cancer

RareCyte

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In this webinar Prof. Sandro Santagata, will reveal how Orion high-plex imaging and the use of this data, is valuable...

Innovation is in its DNA

Mission Bio

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Mission Bio’s Tapestri Tool May Hold the Key to Informing Treatment Options for Multiple Myeloma.

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In vivo tracking of T cells in an inflammatory Bowel disease mouse model

Jan 16, 2017

Inflammatory Bowel Diseases (IBDs) include Crohn’s disease (CD) and ulcerative colitis (UC). They refer to chronic inflammatory disorders of the intestine and/or the colon. In order to better under stand the roles of T cells in the pathogenesis of IBD, several mouse models are available. In particular, they help get precise information about the initiation, induction and regulation of immunopathology induced by T cells. Here, we explore the potential of Cellvizio imaging for the longitudinal monitoring of T cells in an IBD mouse model. The T cell transfer model is especially used to study Crohn’s disease. It has been instrumental in delineating the immunological mechanisms responsible for the induction and regulation of intest inal inflammat ion. For this model, CD4+CD25- T cells injected to SCID mice can generate within 8 weeks an installed bowel inflammation.

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Mauna Kea Technologies

Mauna Kea Technologies manufactures Cellvizio Lab, confocal probe based imaging system, providing cellular-level images with minimal invasiveness for longitudinal studies.

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Cellvizio, a fiber based microscope for observing in real time at cellular scale, features simultaneous, co-registered dual band excitation and detection

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