Discover

Back to filter

Related topics

Pretargeted delivery of PI3K/mTOR small-molecule inhibitor–loaded nanoparticles

Spectral Instruments Imaging

Jun 23, 2021

Overactivation of the PI3K/mTOR signaling has been identified in non-Hodgkin’s lymphoma....

Top 10 Pharma companies have chosen CYTEK for their flow cytometry facility

Cytek Biosciences

Jun 21, 2021

6 of Top 10 Pharma Companies (Based on total group revenues) have chosen CYTEK - full...

Elevated NSD3 histone methylation activity drives squamous cell lung cancer

Spectral Instruments Imaging

Jun 8, 2021

This work identifies NSD3 as a principal 8p11-12 amplicon-associated oncogenic driver in...

A subset of cytotoxic effector memory T cells enhances CAR T cell efficacy in a model of pancreatic

Tonbo Biosciences

May 21, 2021

Tonbo Biosciences flow cytometry reagents & antibodies are manufactured with the highest...

IncuCyte webinar recording: How to measure Immune Cell Killing of Tumor Cells effectively

Sartorius

May 19, 2021

Immuno-oncology (IO) has transformed cancer treatment. The number of treatments in the IO...

White Paper: Immunophenotyping Rare Immune Cells with Laminar Wash AUTO System

Curiox

May 18, 2021

The Laminar Wash (LW) AUTO system consists of a wall-less plate and a laminar flow cell...

Show all topics (10)

In vivo visualization of Candida albicans infections

Oct 30, 2017

Candida yeasts are commensals of human skin and mucosal surfaces but can also cause fungal infections. Candida albicans is a major fungal pathogen and causes life-threatening diseases especially but not limited to immuno-compromised patients. Candidiasis most often develops in the mouth or throat (called oropharyngeal candidiasis or thrush), the vagina (yeast infection) or as invasive candidiasis after entering the bloodstream and thus spreading throughout the body.
The efficacy of drugs to combat fungal infections is limited, as 40 – 60 % of infected patients still die from the disease.
There is a need for novel therapeutic approaches, and this necessitates a detailed knowledge of this fungal pathogens and of its pathogenesis (Sanglard and Odds, 2002). The In-Vivo Xtreme II proved to be a robust system to assess the progression of C. albicans disease in mice. The use of a Sealed Animal Tray is convenient and decreased risks of crosscontamination in our animal facility, especially when several types of pathogens were tested for BLI.

Read more

Scientific paper
Application

Brand profile

Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey