Discover

Back to filter

Related topics

Factors Affecting Petri Dish Condensation in Tissue Culture (CU) Chambers

Percival Scientific

Nov 29, 2023

In this report, we will investigate the effects of infrared lighting, light intensity, stacking, as well as constant...

Visualization of spatial distribution of hemoglobin with various oxygen saturations in small animals

Luxonus

Nov 28, 2023

With the aid of our uniquely developed device and analysis software, our primary objective is to map the spatial...

A fluorescent reporter system for anaerobic thermophiles

COY laboratory products

Nov 27, 2023

Anaerobic microorganisms are key effectors for the sustainable production of biofuels and biochemicals, as they...

Vizgen webinar: spatial relationships in Developmental Biology

Vizgen

Nov 21, 2023

MERFISH integrates spatial transcriptomics technology with high resolution spatial imaging, In this webinar we will...

ScanDrop² Series: Maximum Flexibility in Micro-Volume

Analytik Jena

Nov 6, 2023

The ScanDrop2 from Analytik Jena is the second generation of microvolume spectrophotometers. It´s innovative Butterfly...

NanoCellect webinar: Plant Potential - Gentle Cell Sorting for Enhanced Plant Biology Workflows

NanoCellect

Nov 3, 2023

Gentle cell sorting is a useful tool to increase the efficiency of plant biology workflows that include gene...

SIMOA-based analysis of plasma NFL levels in MCI and AD patients

Quanterix

Nov 3, 2023

The single-molecule array assay (SIMOA)-based detection of neurofilament light (NFL) chain could be useful in...

Single Cell Deposition: the cornerstone of Flow Cytometry for cellular analysis and manipulation

NanoCellect

Nov 2, 2023

One notable technology for harnessing the power of single cell deposition is the NanoCellect WOLF G2 Cell Sorter and N1...

Single cell genotypic and phenotypic analysis of residual disease in acute myeloid leukemia

Mission Bio

Nov 1, 2023

Measurable residual disease (MRD), defined as the population of cancer cells which persists following therapy, serves...

Emulate in vivo conditions – introduce shear flow to your experiments with BioFlux system

Fluxion Biosciences

Oct 31, 2023

Most research is still conducted in vitro without the presence of flow. We use the BioFlux System to give you the...

Show all topics (10)

Method to quantify local force distribution within biomolecular systems

May 24, 2018

By using optical tweezers coupled with fluorescence microscopy, Dr. King et al. (2018) studied the ability of cyanine intercalator dyes to quantify the molecular tension within biomolecular structures. They found that intercalators can be used in biomolecular systems in real-time to measure the tension locally and to determine how applied forces are partitioned. As an example, the authors demonstrated that stretched and entwined DNA structures can generate transient DNA-DNA interactions that mimic DNA bridges, by measuring the tension and local force distribution within the structures.

Scientific paper
Technical breakthrough
Product news

Brand profile

LUMICKS

Optical tweezers, Confocal microscopy, STED nanoscopy, Acoustic force spectroscopy for single-molecule biophysics. 

Related products

Acoustic Force Spectroscopy is a single-molecule, lab-on-a-chip technology in which acoustic waves are used to exert forces on thousands of biomolecules.

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey