Discover

Back to filter

Related topics

Download today your IsoPlexis e-book: understanding immune Cell Function In Cancer

IsoPlexis

Dec 1, 2021

Understanding complex immune-cancer interactions is critical to identifying therapeutic targets, devising novel avenues...

Extensive assessment of Cytokine production on the NovoCyte Penteon flow cytometer

Agilent technologies

Nov 29, 2021

Cytokines are small molecules essential for immune cell response to activation by pathogens, autoimmunity, or...

IsoPlexis technology: accelerating decisions in immunotherapy with predictive single-cell response

IsoPlexis

Nov 26, 2021

The IsoLight is a hub for comprehensive functional profiling of each cell type across a large assay menu of single-cell...

Customer Story: Automation at DKMS LIFE SCIENCE LAB

Analytik Jena

Nov 25, 2021

How DKMS LIFE SCIENCE LAB is Supporting the Fight against Leukemia with New Processes and Automation

Accelerating AML Research Through Single-cell Multi-omics- integrate seamlessly into existing NGS

Mission Bio

Nov 25, 2021

Dr. Linde Miles Memorial Sloan Kettering Cancer Center about her research, use of the Tapestri as a single-cell...

The New Standard in Automated Nucleic Acid Extraction- InnuPure C16

Analytik Jena

Nov 23, 2021

Fully automatic nucleic acid extraction of up to 16 samples, sophisticated kit architecture for easy handling, more...

Discover the advanced Detector Technology in Agilent NovoCyte flow cytometers

Agilent technologies

Nov 18, 2021

This technical overview describes advancements in detector technology, and highlights examples where optimal signal...

Introducing isoLight system - Automated Cellular Proteomics hub

IsoPlexis

Nov 16, 2021

The IsoLight is a hub for comprehensive functional profiling of each cell type across a large assay menu of single-cell...

Introducing Cytek NEW 25-Color Immunoprofiling Assay & Kit!

Cytek Biosciences

Nov 15, 2021

To unleash the power of the Cytek full spectrum cytometry system, Cytek scientists designed and developed the 25-Color...

How to Improve Your Viral Nucleic Acid Extraction Processes

Analytik Jena

Sep 6, 2021

High-Throughput Extraction with CyBio FeliX

Show all topics (10)

Method to quantify local force distribution within biomolecular systems

May 24, 2018

By using optical tweezers coupled with fluorescence microscopy, Dr. King et al. (2018) studied the ability of cyanine intercalator dyes to quantify the molecular tension within biomolecular structures. They found that intercalators can be used in biomolecular systems in real-time to measure the tension locally and to determine how applied forces are partitioned. As an example, the authors demonstrated that stretched and entwined DNA structures can generate transient DNA-DNA interactions that mimic DNA bridges, by measuring the tension and local force distribution within the structures.

Scientific paper
Technical breakthrough
Product news

Brand profile

LUMICKS

Optical tweezers, Confocal microscopy, STED nanoscopy, Acoustic force spectroscopy for single-molecule biophysics. 

Related products

Live, simultaneous and correlative visualization and manipulation of molecular interactions with sub-picoNewton force resolution and sub-nm position resolution.

show detail

The first dedicated optical tweezers instrument specifically developed for high-resolution single-molecule force spectroscopy research.

show detail

Acoustic Force Spectroscopy is a single-molecule, lab-on-a-chip technology in which acoustic waves are used to exert forces on thousands of biomolecules.

show detail

We supply and support Life-Science Technologies in the territory of Central and Eastern Europe.

Czech Republic

Slovakia

Hungary

Poland

Croatia

Slovenia

Serbia

Romania

Bulgaria

Latvia

Lithuania

Estonia

Russia

Ukraine

Belarus

Turkey