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Introducing Cytek Human Leukocyte Kit, the first ever 15-color lyse no-wash assay

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This kit has been designed to enumerate all major leukocyte subsets and it mirrors and expands on those identified in a...

Immunofluorescence Imaging for Rare Cell Detection with CyteFinder II

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Flash news - did you know, that you can use Singulator S100 also for plant research?

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Extensive assessment of Cytokine production on the NovoCyte Advanteon flow cytometer

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Microfluidic cell sorter sample preparation for genomic assays

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CellRad+ benchtop X-Ray irradiator

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Introducing Cytek Cloud

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Cytek Cloud is the new digital ecosystem that supports full spectrum flow cytometry research from panel design to data...

See More, Sort More with Cytek Full Spectrum Systems

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Still wondering whether to join the shift to full spectrum cytometry?  Easily transfer assays from your Cytek Northern...

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Method to quantify local force distribution within biomolecular systems

May 24, 2018

By using optical tweezers coupled with fluorescence microscopy, Dr. King et al. (2018) studied the ability of cyanine intercalator dyes to quantify the molecular tension within biomolecular structures. They found that intercalators can be used in biomolecular systems in real-time to measure the tension locally and to determine how applied forces are partitioned. As an example, the authors demonstrated that stretched and entwined DNA structures can generate transient DNA-DNA interactions that mimic DNA bridges, by measuring the tension and local force distribution within the structures.

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LUMICKS

Optical tweezers, Confocal microscopy, STED nanoscopy, Acoustic force spectroscopy for single-molecule biophysics. 

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Acoustic Force Spectroscopy is a single-molecule, lab-on-a-chip technology in which acoustic waves are used to exert forces on thousands of biomolecules.

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