With BioFlux System for live cell analysis under shear flow and IsoFlux System for circulating tumor cell analysis, Fluxion Biosciences turn power of benchtop cellular analysis with advanced tools to automate complex assays.
Discover
Related topics
CellRad+ benchtop X-Ray irradiator
Dec 9, 2022
New CellRad+ benchtop irradiator for biological samples is coming with higher voltage and continue exposure for 180...
Dec 1, 2022
Cytek Cloud is the new digital ecosystem that supports full spectrum flow cytometry research from panel design to data...
See More, Sort More with Cytek Full Spectrum Systems
Nov 28, 2022
Still wondering whether to join the shift to full spectrum cytometry? Easily transfer assays from your Cytek Northern...
Introducing MARS system : revolutionary solution for your workflow of cell separation and enrichment
Oct 7, 2022
The MARS family of instruments provides a breakthrough solution to complete the workflow of cell separation and...
Introducing RareCyte Orion, integrating Spatial Biology with Multiplex Imaging
Sep 13, 2022
Orion, the highly multiplexed fluorescent imaging system, empower investigators to unlock spatial context for key...
xCELLigence eSight - Imaging & Impedance in real-time inside your incubator
Aug 22, 2022
The xCELLigence RTCA eSight enables comprehensive insight into cell health, cell behavior, cell function and cell...
Standardize tumor sample preparation and reduce background with Curiox laminar wash system
Aug 10, 2022
Laminar Wash technology offers a gentle alternative that can improve yield and data quality, particularly of rare cell...
Developing a 43 color panel on Cytek Aurora using Laminar Wash for sample prep
Aug 2, 2022
Successfully executing a 43 color panel is a technically demanding task. One that is made more difficult when there are...
New Center of Excellence, located at the Josep Carreras Leukaemia Research Institute
Jul 12, 2022
Mission Bio is a life sciences company that accelerates discoveries and cures for a wide range of diseases by equipping...
Intoducing spheroOne: Automated sorting and isolation of single spheroids and organoids
Jun 21, 2022
spheroONE is an innovative single large-particle sorter and dispenser which revolutionizes 3D cellular models handling....
Mar 15, 2016
Two kits have been launched for enhanced CTC isolation and recovery that are designed to work exclusively with the IsoFlux Liquid Biopsy system. The new kits include the Enhanced Recovery Kit and the EMT Kit. The Enhanced Recovery kit adds EGFR to the traditional EpCAM antibody, and the EMT kit includes EpCAM, EGFR, and two proprietary mesenchymal phenotype antibodies.
The IsoFlux System uses blood to perform a real-time “liquid biopsy” of the patient’s cancer using the recovered CTCs. The high efficiency and high purity of the recovered cells allows for the use of highly multiplexed analyses such as next-generation sequencing (NGS) for cancer mutational profiling. Screening for a broad range of cancer biomarkers via NGS will help guide treatment decisions using an emerging class of precision cancer therapies. The introduction of the new CTC kits increases the recovery efficiency of CTCs, further improving the IsoFlux system’s industry-leading sensitivity.
According to Fluxion’s CTO, Dr. Cristian Ionescu-Zanetti, the new kits provide significant gains in cell recovery and open new avenues in clinical research. “It is well known that EpCAM expression levels vary greatly across cancer types and within cancer cell populations. This can limit the recovery efficiency in very low-expressing cancer types, such as lung and pancreatic cancers. Although the IsoFlux system’s high-sensitivity microfluidic cell recovery performs well on these low expressers when targeting EpCAM, the new kits provide a higher level of performance while enabling recovery of a wider spectrum of cell types. The EMT kit is the first commercially available that targets the mesenchymal cell phenotype for CTCs that have undergone EMT, considered to be a potential contributor to metastasis.”
The Enhanced Recovery Kit and EMT Kit are already available and can be used on all existing IsoFlux systems without modification.
Brand profile
With BioFlux System for live cell analysis under shear flow and IsoFlux System for circulating tumor cell analysis, Fluxion Biosciences turn power of benchtop cellular analysis with advanced tools to automate complex assays.
More info at:
www.fluxionbio.com