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Theranostics: From Mice to Men and Back

MOLECUBES

Jun 25, 2024

Recorded webinar
Presenters: Prof. Dr. Ken Herrmann and Prof. Dr. Katharina Lückerath – Moderator: Hannah Notebaert

Automated Purification of Viral DNA and RNA from Biological Samples usingZymo Research Quick-DNA/RNA

Analytik Jena

Jun 14, 2024

The Quick DNA/RNA Viral MagBead Kit from Zymo has been automated with the Cybio FeliX pipetting robot from Analytik...

DNA Amplicon Library Preparation for Illumina® Sequencing

Analytik Jena

Jun 12, 2024

The precision of temperature control, efficient heating and cooling rates, and excellent temperature homogeneity across...

X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization

Precision X-Ray

Jun 5, 2024

Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...

High-frequency Ultrasound System For Preclinical Imaging

S-Sharp

May 13, 2024

The Prospect T1 is an innovative high-frequency ultrasound system designed specifically for in vivo preclinical imaging...

April 2024 publication revealing benefits of using intravital microscopy in trascriptomics studies

IVIM Technology

May 7, 2024

Transcriptional activation of Bmal1 drives the inflammatory activity of monocytes by modulating mitochondrial unfolded...

Omics Studies of Tumor Cells under Microgravity Conditions

CelVivo

May 6, 2024

It is important for the analysis of data from space experiments to distinguish unspecific stress reactions from...

Column-Free CD14+ Monocyte Isolation using 50nm Superparamagentic Beads on MARS® Bar

Applied Cells

Apr 25, 2024

The MARS® Bar Magnetic Separation Platform is a closed and automated isolation for cell therapy development and...

Spatial and temporal profiling of the complement system uncovered novel functions of the alternative

Vizgen

Apr 24, 2024

Mounting evidence implicated the classical complement pathway (CP) in normal brain development, and the pathogenesis of...

Study finds\; Plasma p-tau217, p-tau181, and NfL as early indicators of dementia risk of AD

Quanterix

Apr 24, 2024

Blood biomarkers showed values for predicting future cohnitive impairment. Evidence from the community-based cohort was...

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Optical advances – the latest developments in Preclinical imaging

Aug 5, 2016

Preclinical in vivo molecular imaging is widely regarded as a key tool within the drug discovery and development pipeline, giving researchers clear visibility of cellular changes at a molecular level. Techniques – or modalities – such as optical, PET and SPECT imaging provide high specificity and wide applicability, as well as the ability to monitor several molecular events and identify key molecular markers. The result is a deeper understanding of disease progression, and the mode of action and pharmacokinetics of potential therapeutics.

If we consider small animal optical imaging systems specifically, these now enable researchers to combine a number of imaging modalities using the same instrument, thereby paving the way for a better understanding of physiological and disease mechanisms in the preclinical setting. For example, one such system provides five imaging modalities as standard, allowing for co-registration of molecular events with access to bioluminescence, multispectral VIS-NIR fluorescence, unique direct radioisotopic imaging, and Cerenkov radiation. A high speed digital X-ray scanner adds to the functional images with morphological features.

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Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

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Albira combines PET, SPECT and CT imaging in a unique and extremely powerful way

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