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Real-time and quantitative analysis of Macrophage Phagocytosis with RTCA eSight

Agilent technologies

Feb 23, 2024

The eSight is currently the only instrument that interrogates cell health and behavior using cellular
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Visualization of Tumor-Related Blood Vessels in Small Animals by Photoacoustic 3D Imaging System

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In Vivo Label-Free Observation of Tumor-Related Blood Vessels in Small Animals Using a Newly Designed Photoacoustic 3D...

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Evaluation with BLI of synthetic immune checkpoint engagers in allogenic mice

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Synthetic immune checkpoint engagers protect HLA-deficient iPSCs and derivatives from innate immune cell cytotoxicity

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Doctoral Thesis, Stefan van Hoof, Maastricht University 2019

IVM and single cell transcriptomic analysis for engraftment of mesenchymal stem cells

IVIM Technology

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Small animal DXA instrument comparison and validation 2024

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Flexible multiplex panel design with new Orion Reagents

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Preclinical PET imaging in studies of candidate therapeutics

Jun 22, 2017

Clinical and preclinical non-invasive PET imaging is employed in the development and validation of therapeutic agents for cancer and neurological disorders, and a range of other diseases. Reported studies have used numerous agents including FDG, FLT, FMISO and FAZA as early biomarkers of drug efficacy. Preclinical PET imaging has been proven in studies of therapeutic targeting and biodistribution, drug target interactions, pharmacodynamics and toxicology. These methods have helped facilitate the development of therapeutic agents that are now clinically available. Probably two of the most common uses of preclinical PET imaging in drug discovery are studies of compound targeting and biodistribution and therapeutic efficacy. In the article, you can find a brief introduction to preclinical PET imaging for such studies.

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Scientific paper
Application

Related technologies: PET, SPECT, CT

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Bruker Biospin

Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.

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Albira combines PET, SPECT and CT imaging in a unique and extremely powerful way

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