Essen BioScience (part of Sartorius), is a team of engineers and biologists with deep expertise in cell-based assays. They invent, manufacture, supply and support cell-based assay instrumentation, reagents and protocols.
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Early immune response in mice immunized with inactivated vaccine against SARS-CoV-2
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Curiox webinar - how to retain more cells for Single Cell Sequencing and proteogenomics ?
Nov 19, 2020
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Discover the new NovoCyte Penteon - when exceptional performance meets simplicity
Nov 18, 2020
The NovoCyte Penteon flow cytometer builds on its successful predecessor, the NovoCyte. You now have the flexibility to...
Cellular stress induces erythrocyte assembly and promotes microangiopathy
Dec 19, 2018
Microangiopathy with subsequent organ damage represents a major complication in several diseases. The mechanisms...
The need for ultra high field magnetic resonance imaging
Dec 17, 2018
MRI is a noninvasive imaging technology that is known for its superior soft tissue contrast and ability to provide...
NovoCyte Quanteon webinar: In-depth cell Proliferation through new advances in flow cytometry
Dec 11, 2018
Cell proliferation is one of the most fundamental biological processes in biology. Many of the traditional assays to...
Webinar: early detection of metabolic remodeling in pressure overload left ventricle Hypertrophy
Nov 28, 2018
Do you already heard the hypothesis that metabolic changes in the heart may precede and even trigger structural and...
Bioflux webinar: Blockade of CD62L inhibits CLL cell interaction with vascular endothelium
Nov 22, 2018
CD62L (L-selectin) is a key adhesion molecule that promotes cell tethering and rolling along the vascular endothelium...
IncuCyte neuronal activity assay
Nov 13, 2018
The generation and maturation of neuronal networks are necessary characteristics of neurogenesis, providing...
Quantification of cell migration and invasion using the IncuCyte chemotaxis assay
Mar 15, 2016
Effective in vitro models of directed cell migration, or chemotaxis, are necessary for both basic research and drug discovery. This application note describes a new methodology for studying chemotactic cell migration and invasion using the IncuCyte ZOOM Live-Cell Imaging system. This novel approach enables real-time visualization and automated analysis of chemotactic migration and invasion in a 96-well format within a tissue culture incubator.
By incorporating a made-for-purpose, optically clear membrane into a transmembrane geometry, the IncuCyte chemotaxis assay facilitates the label-free visualization and quantitation of directed cell migration and invasion. The design of the IncuCyte ClearView 96-Well Cell Migration Plate ensures a stable gradient over 72 hours and requires only 1,000–5,000 cells per well. In contrast to traditional Boyden-chamber methodologies, cells in the IncuCyte chemotaxis assay are required to migrate on a biologically relevant surface toward the chemoattractant. The result is 96 wells of reproducible kinetic data supported by images and movies, requiring very few cells and minimal hands-on time.
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