Essen BioScience (part of Sartorius), is a team of engineers and biologists with deep expertise in cell-based assays. They invent, manufacture, supply and support cell-based assay instrumentation, reagents and protocols.
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Recent publication of in-vivo two-photon intravital imaging study targeting mouse kidney
May 22, 2023
In vivo longitudinal 920 nm two-photon intravital kidney imaging of a dynamic 2,8-DHA crystal
formation and...
Webinar: Multimodal tissue imaging and machine learning to advance precision medicine
May 17, 2023
Join us for this webinar to learn how the Orion spatial biology imaging platform was used to identify prognostic...
May 5, 2023
Decision to improve the output in a lab is always taken based on knowledge and workflow needs. But final decision to...
Real-Time and Quantitative Analysis of Macrophage Phagocytosis with RTCA eSight
May 4, 2023
The eSight is currently the only instrument that interrogates cell health and behavior using cellular
impedance...
Revolutionize your Flow Cytometry and Sorting workflow with Cytek Biosciences
May 3, 2023
Using full spectrum flow cytometry, Cytek systems ( RUO and CE-IVD) detect the entire fluorochrome emission, allowing...
Thermal Shift Assay using SYPRO Orange to Detect Protein Melting Temperatures
May 2, 2023
The thermal shift assay is based on temperature-induced denaturation and can be monitored using SYPRO Orange. This...
A deep learning and Monte Carlo based framework for bioluminescence imaging center Maastro
Apr 20, 2023
"In this paper,we developed a framework using deep learning for bioluminescence-based targeting for GBM animal...
Gentle sorting of microbial cells and sub-micron particles using WOLF sorter
Apr 18, 2023
While most modern applications of flow cytometry may focus on cells of eukaryotic origin, the first flow analyzers were...
InAlyzer to evaluate G6PD activity in relation with frailty
Mar 28, 2023
InAlyzer is body densitometry instrument for lab animals, equipped with 2 X-Ray sources and able to provide valuable...
Cardiomyocyte isolation using Cellenion’s cellenONE instrument
Mar 24, 2023
The cellenONE platform is ideal for the isolation of fragile and heterogeneous cell size populations, such as...
Quantification of cell migration and invasion using the IncuCyte chemotaxis assay
Mar 15, 2016
Effective in vitro models of directed cell migration, or chemotaxis, are necessary for both basic research and drug discovery. This application note describes a new methodology for studying chemotactic cell migration and invasion using the IncuCyte ZOOM Live-Cell Imaging system. This novel approach enables real-time visualization and automated analysis of chemotactic migration and invasion in a 96-well format within a tissue culture incubator.
By incorporating a made-for-purpose, optically clear membrane into a transmembrane geometry, the IncuCyte chemotaxis assay facilitates the label-free visualization and quantitation of directed cell migration and invasion. The design of the IncuCyte ClearView 96-Well Cell Migration Plate ensures a stable gradient over 72 hours and requires only 1,000–5,000 cells per well. In contrast to traditional Boyden-chamber methodologies, cells in the IncuCyte chemotaxis assay are required to migrate on a biologically relevant surface toward the chemoattractant. The result is 96 wells of reproducible kinetic data supported by images and movies, requiring very few cells and minimal hands-on time.
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