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Quantitative two-photon microscopy imaging analysis of human skin

Jul 1, 2021

In this work, was achieved a cellular-level depth-defined visualization of fluorophore-labelled human epidermal growth factor (EGF) transdermally delivered to human skin by using encapsulation with common liposomes and newly fabricated multi-lamellar nanostructures using a custom-design two-photon microscopy system. It was able to generate 3D reconstructed images displaying the distribution of human EGF inside the human skin sample with high-resolution. Based on a depthwise fluorescence intensity profile showing the permeation of human EGF, a quantitative analysis was perform

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Related technologies: IntraVital Microscopy

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IVIM Technology

IntraVital Microscopy is a technique that enables you to directly observe the movement of live cells that make up living tissue in vivo.

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