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The chicken chorioallantoic membrane as a low-cost, high-throughput model for cancer imaging

Precision X-Ray

Apr 4, 2024

Here, we assessed the chicken chorioallantoic membrane (CAM) as an alternative to mice for preclinical cancer imaging...

A microthrombus-driven fixed-point cleaved nanosystem for preventing post-thrombolysis recurrence

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A thrombin-responsive and fixed-point cleaved Fu@pep-CLipo was developed for highly efficient and precise thrombolysis...

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In this webinar Prof. Sandro Santagata, will reveal how Orion high-plex imaging and the use of this data, is valuable...

Innovation is in its DNA

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Discover Yokogawa CellVoyager CQ1: Benchtop High-Content Analysis System

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Unlike flow cytometers, the CellVoyager CQ1 confocal quantitative image cytometer does not require pretreatment such as...

Real-time and quantitative analysis of Macrophage Phagocytosis with RTCA eSight

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Visualization of Tumor-Related Blood Vessels in Small Animals by Photoacoustic 3D Imaging System

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In Vivo Label-Free Observation of Tumor-Related Blood Vessels in Small Animals Using a Newly Designed Photoacoustic 3D...

Therapeutic effects of mesenchymal stem cells in myocardial infarction

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Radiation planning for image guided preclinical radiotherapy

Jan 12, 2024

The work of this thesis advances techniques that improve the accuracy and versatility of preclinical radiation planning, to enable planning and delivery of more flexible and complex dose distributions for preclinical radiotherapy. Monte Carlo based radiation planning is introduced to achieve accurate dose calculation at the appropriate scale and photon energies used. Abeam-on time optimization framework is developed to achieve a higher degree of planning automation which is essential when moving to more complex beam delivery protocols. These techniques are extended by using multi angled irradiation with fixed beam shape and size,and subject translation during irradiation to enable more conformal dynamic target  irradiation. The developed methods are applied to enable localized irradiation for an orthotopic glioblastoma mouse model. All developed knowledge is rapidly distributed to research institutes worldwide through successful valorisation.

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Related technologies: X-ray irradiation

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