Phagocytosis is a specific form of endocytosis by which cells engulf and internalize solid matter. Macrophages, neutrophils and immature dendritic cells are the major phagocytic cells of the immune system and specialize in this process. Phagocytosis is a key mechanism by which micro-organisms are contained, killed and processed for antigen presentation and represents a vital facet of the innate immune response to pathogens.
The IncuCyte Phagocytosis Assay provides real-time visualization and analysis of the internalization of bioparticles using pH sensitive-conjugated probes, and is ideal for monitoring phagocytosis of bacterial Gram positive, Gram negative or yeast-derived pathogens by immune cells.