Bruker is a performace leader in preclinical imaging instrumentation. Bruker offers nine imaging modalities: PET, SPECT, CT, MRI, MPI, fluorescence, luminiscence, radioisotipic imaging and X-ray.
Discover
Back to filter
Show all topics (10)
Related topics
Intoducing spheroOne: Automated sorting and isolation of single spheroids and organoids
Jun 21, 2022
spheroONE is an innovative single large-particle sorter and dispenser which revolutionizes 3D cellular models handling....
Outstanding post-sort sample recovery on the WOLF Cell Sorter
Jun 14, 2022
The new WOLF G2 instrument has significantly expanded the capabilities of gentle benchtop microfluidic cell sorting...
Incucyte AI module: Advanced Label-Free Classification Analysis
Jun 6, 2022
Monitor adherent cell morphology changes objectively to determine live/dead cell counts or classify cells based on...
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters
Jun 3, 2022
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine...
Intoducing cellenONE: The revolutionary Single Cell isolator
May 25, 2022
A revolutionary platform based on sciDROP PICO precision dispensing technology and coupled with advanced image...
Advances in Leukemia research using shear flow and Bioflux system
May 24, 2022
Leukemia is a rare cancer with many subtypes. The production of abnormal leukocytes create disruptions in the immune...
May 4, 2022
A prodigy incorporating a unique combination of patent-pending innovative technologies that takes flow cytometry to the...
Introducing Celloger Mini Plus: Automated and compact Live cell imaging inside your incubator
Apr 11, 2022
We are happy to introduce new Celloger Mini Plus, automated live cell imaging system! Click the video below to find out...
CQ1 live-cell confocal system: revealing the pathophysiology of COVID-19 infection
Mar 21, 2022
Yokogawa decided to support the world’s fight against COVID-19, scientifically cooperating with research facilities...
In-vivo webinar: a versatile use of SPECT/CT in the development of theranostic tracers
Mar 9, 2022
Combining (preclinical) imaging and targeted therapy, is the basis of theranostics. In this webinar, Dr. Florea will...
Red-shifted firefly luciferase optimized for Candida albicans in vivo bioluminescence imaging
Sep 15, 2017
The authors of this study attempted to compare the performance of BLI in the present study with that published using the systemic infection model and light detection in the region of the kidneys. They estimated that a lower limit of detection for BLI (50 photon/s/mm2) corresponded to of about 200 CFU/kidney with the instrumentation used here (in-vivo Xtreme II). Given numbers published by Jacobsen et al. (2014) (100 photon/s/mm2 for 3,600 CFU/kidney), this suggests that the method used here increases at least by 4- to 8-fold the sensitivity of C. albicans detection.
This performance can be attributed to several factors including (i) the type of luciferase used (Mut2 has better tissue penetration capacities than the wild type luciferase) and (ii) technical differences provided by the luminescence acquisition of instruments. This performance is even more remarkable when taking in account that BLI data was collected here from animals contained in Sealed Optical Imaging Trays, which may create another obstacle of emitted light to the high sensitivity camera.
Related technologies: Fluorescence, luminescence, X-ray, radiographic imaging
Brand profile
