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Pretargeted delivery of PI3K/mTOR small-molecule inhibitor–loaded nanoparticles

Spectral Instruments Imaging

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Overactivation of the PI3K/mTOR signaling has been identified in non-Hodgkin’s lymphoma....

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Assessment of precise genetic edits. Analysis of the clonal structure & co-mutations of AEL. Use of CRISPR and...

SARS-CoV-2 detection workflow in wastewater - Analytik Jena and project in Japan

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In 2020 Analytik Jena real-time PCR thermal cyclers of the qTOWER³ series even supported one of the first SARS-CoV-2...

Cytek Spectral cytometers : taking science one step further with 200+ Publications

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Cytek Aurora is helping researchers around the world take their science further. See how...

Observe the movement of live cells that make up living tissue in vivo!

IVIM Technology

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IntraVital Microscopy is a technique that enables you to directly observe the movement of live cells that make up...

Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice

Precision X-Ray

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Radio-active sources have been used routinely for the preconditioning in humanized mouse...

Advances in Leukemia research using shear flow and Bioflux system

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Leukemia is a rare cancer with many subtypes. The production of abnormal leukocytes...

Do you have our CellRad benchtop irradiator? It’s the only one on the market!

Precision X-Ray

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The CellRad is a smaller, simpler, safer, and more cost effective alternative to...

Dosimetric characterization of an X-ray irradiator for use with cells

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This study aims to characterize an X-ray irradiator for use with cells using its internal...

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Single-cell twitching chemotaxis in developing biofilms

Jan 24, 2017

Here we use microfluidic chemical gradients and massively parallel automated tracking to study the behavior of the pathogen Pseudomonas aeruginosa during early biofilm development. We show that individual cells can efficiently move toward chemo-attractants using pili-based “twitching” motility and the Chp chemosensory system. Moreover, we discovered the behavioral mechanism underlying this surface chemotaxis: cells reverse direction more frequently when moving away from chemoattractant sources. These corrective maneuvers are triggered rapidly, typically before a wayward cell has ventured a fraction of a micron. Our work shows that single bacteria can direct their motion with submicron precision and reveals the hidden potential for chemotaxis within bacterial biofilms.

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Fluxion Biosciences

With BioFlux System for live cell analysis under shear flow and IsoFlux System for circulating tumor cell analysis, Fluxion Biosciences turn power of benchtop cellular analysis with advanced tools to automate complex assays.

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