With BioFlux System for live cell analysis under shear flow and IsoFlux System for circulating tumor cell analysis, Fluxion Biosciences turn power of benchtop cellular analysis with advanced tools to automate complex assays.
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Pretargeted delivery of PI3K/mTOR small-molecule inhibitor–loaded nanoparticles
Jun 23, 2021
Overactivation of the PI3K/mTOR signaling has been identified in non-Hodgkin’s lymphoma....
Elevated NSD3 histone methylation activity drives squamous cell lung cancer
Jun 8, 2021
This work identifies NSD3 as a principal 8p11-12 amplicon-associated oncogenic driver in...
Single-cell DNA Analysis of a Novel Acute Erythroid Leukemia CRISPR Induced Mouse Model
May 9, 2021
Assessment of precise genetic edits. Analysis of the clonal structure & co-mutations of AEL. Use of CRISPR and...
SARS-CoV-2 detection workflow in wastewater - Analytik Jena and project in Japan
May 8, 2021
In 2020 Analytik Jena real-time PCR thermal cyclers of the qTOWER³ series even supported one of the first SARS-CoV-2...
Cytek Spectral cytometers : taking science one step further with 200+ Publications
Apr 26, 2021
Cytek Aurora is helping researchers around the world take their science further. See how...
Observe the movement of live cells that make up living tissue in vivo!
Apr 12, 2021
IntraVital Microscopy is a technique that enables you to directly observe the movement of live cells that make up...
Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice
Dec 29, 2020
Radio-active sources have been used routinely for the preconditioning in humanized mouse...
Advances in Leukemia research using shear flow and Bioflux system
Dec 10, 2020
Leukemia is a rare cancer with many subtypes. The production of abnormal leukocytes...
Do you have our CellRad benchtop irradiator? It’s the only one on the market!
Dec 9, 2020
The CellRad is a smaller, simpler, safer, and more cost effective alternative to...
Dosimetric characterization of an X-ray irradiator for use with cells
Dec 4, 2020
This study aims to characterize an X-ray irradiator for use with cells using its internal...
Single-cell twitching chemotaxis in developing biofilms
Jan 24, 2017
Here we use microfluidic chemical gradients and massively parallel automated tracking to study the behavior of the pathogen Pseudomonas aeruginosa during early biofilm development. We show that individual cells can efficiently move toward chemo-attractants using pili-based “twitching” motility and the Chp chemosensory system. Moreover, we discovered the behavioral mechanism underlying this surface chemotaxis: cells reverse direction more frequently when moving away from chemoattractant sources. These corrective maneuvers are triggered rapidly, typically before a wayward cell has ventured a fraction of a micron. Our work shows that single bacteria can direct their motion with submicron precision and reveals the hidden potential for chemotaxis within bacterial biofilms.
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