With BioFlux System for live cell analysis under shear flow and IsoFlux System for circulating tumor cell analysis, Fluxion Biosciences turn power of benchtop cellular analysis with advanced tools to automate complex assays.
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Cellular stress induces erythrocyte assembly and promotes microangiopathy
Dec 19, 2018
Microangiopathy with subsequent organ damage represents a major complication in several diseases. The mechanisms...
The need for ultra high field magnetic resonance imaging
Dec 17, 2018
MRI is a noninvasive imaging technology that is known for its superior soft tissue contrast and ability to provide...
The most advanced software for preclinical imaging research
Nov 7, 2018
Modern imaging laboratories hosting PET/MR instruments profit from the fully integrated common imaging platform...
Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs
Oct 12, 2018
Drug delivery by nanocarriers (NCs) has long been stymied by dominant liver uptake and limited target organ deposition,...
Adenovirus type B detection using the xxpress qPCR thermal cycler
Sep 17, 2018
The ultrafast xxpress qPCR thermal cycler through performing standard dilution series and multiplex qPCR experiments is...
Diagnosis of Acute Cellular Rejection Using Probe-Based Confocal Laser Endomicroscopy in Lung
Sep 3, 2018
Mauna Kea Technologies announced the publication of a prospective multicenter study that demonstrates the potential of...
Aug 9, 2018
We bring you the latest KOL interview on the Albira Si PET/SPECT/CT from Prof. John Prior, CHUV Lausanne. He describes...
Differentation displacement in acute myeloid leukemia through enhancer activation
Aug 7, 2018
Blast cell differentation is inhibitited by pharmacological targeting of lysine specific demethylase 1 (LSD1). In this...
Dynamic PET imaging and special focus in cardiac kinetic analysis
Aug 1, 2018
Micro-computed tomography, or micro-CT, is being employed by a rapidly increasing number of laboratories for bone...
Novel insights on the mechanical properties of IFs using LUMICKS’ technology
Jul 30, 2018
The journal Science Advances has recently published the paper ‘Viscoelastic properties of vimentin originate from...
Single-cell twitching chemotaxis in developing biofilms
Jan 24, 2017
Here we use microfluidic chemical gradients and massively parallel automated tracking to study the behavior of the pathogen Pseudomonas aeruginosa during early biofilm development. We show that individual cells can efficiently move toward chemo-attractants using pili-based “twitching” motility and the Chp chemosensory system. Moreover, we discovered the behavioral mechanism underlying this surface chemotaxis: cells reverse direction more frequently when moving away from chemoattractant sources. These corrective maneuvers are triggered rapidly, typically before a wayward cell has ventured a fraction of a micron. Our work shows that single bacteria can direct their motion with submicron precision and reveals the hidden potential for chemotaxis within bacterial biofilms.
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