With BioFlux System for live cell analysis under shear flow and IsoFlux System for circulating tumor cell analysis, Fluxion Biosciences turn power of benchtop cellular analysis with advanced tools to automate complex assays.
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Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice
Dec 29, 2020
Radio-active sources have been used routinely for the preconditioning in humanized mouse...
Advances in Leukemia research using shear flow and Bioflux system
Dec 10, 2020
Leukemia is a rare cancer with many subtypes. The production of abnormal leukocytes...
Do you have our CellRad benchtop irradiator? It’s the only one on the market!
Dec 9, 2020
The CellRad is a smaller, simpler, safer, and more cost effective alternative to...
Dosimetric characterization of an X-ray irradiator for use with cells
Dec 4, 2020
This study aims to characterize an X-ray irradiator for use with cells using its internal...
Early immune response in mice immunized with inactivated vaccine against SARS-CoV-2
Nov 23, 2020
The development of a vaccine against COVID-19 is a hot topic for many research...
Cellular stress induces erythrocyte assembly and promotes microangiopathy
Dec 19, 2018
Microangiopathy with subsequent organ damage represents a major complication in several diseases. The mechanisms...
The need for ultra high field magnetic resonance imaging
Dec 17, 2018
MRI is a noninvasive imaging technology that is known for its superior soft tissue contrast and ability to provide...
The most advanced software for preclinical imaging research
Nov 7, 2018
Modern imaging laboratories hosting PET/MR instruments profit from the fully integrated common imaging platform...
Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs
Oct 12, 2018
Drug delivery by nanocarriers (NCs) has long been stymied by dominant liver uptake and limited target organ deposition,...
Adenovirus type B detection using the xxpress qPCR thermal cycler
Sep 17, 2018
The ultrafast xxpress qPCR thermal cycler through performing standard dilution series and multiplex qPCR experiments is...
Single-cell twitching chemotaxis in developing biofilms
Jan 24, 2017
Here we use microfluidic chemical gradients and massively parallel automated tracking to study the behavior of the pathogen Pseudomonas aeruginosa during early biofilm development. We show that individual cells can efficiently move toward chemo-attractants using pili-based “twitching” motility and the Chp chemosensory system. Moreover, we discovered the behavioral mechanism underlying this surface chemotaxis: cells reverse direction more frequently when moving away from chemoattractant sources. These corrective maneuvers are triggered rapidly, typically before a wayward cell has ventured a fraction of a micron. Our work shows that single bacteria can direct their motion with submicron precision and reveals the hidden potential for chemotaxis within bacterial biofilms.
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