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High quality Bioluminescence and X-Ray analysis in lung squamous cell carcinoma

Spectral Instruments Imaging provides unrivaled sensitivity for bioluminescence, fluorescence and X-Ray for in vivo imaging analysis.

Jul 21, 2021

Scientific paper
Application

Pretargeted delivery of PI3K/mTOR small-molecule inhibitor–loaded nanoparticles

Overactivation of the PI3K/mTOR signaling has been identified in non-Hodgkin’s lymphoma. BEZ235 is an effective dual PI3K/mTOR inhibitor, but it was withdrawn from early-phase clinical trials owing to poor solubility and on-target/off-tumor toxicity.

Jul 3, 2021

Scientific paper
Application

Single-cell DNA Analysis of a Novel Acute Erythroid Leukemia CRISPR Induced Mouse Model

Assessment of precise genetic edits. Analysis of the clonal structure & co-mutations of AEL. Use of CRISPR and scDNA-seq for disease modeling.

May 9, 2021

Scientific paper
Application

Observe the movement of live cells that make up living tissue in vivo!

IntraVital Microscopy is a technique that enables you to directly observe the movement of live cells that make up living tissue in vivo.

Apr 12, 2021

Scientific paper
Product news

Quantitative two-photon microscopy imaging analysis of human skin

Transdermal skin delivery is a method to transport various topical formulations to a deeper skin layer non-invasively. However, it cannot reveal a detailed depth-dependent distribution profile of transdermally delivered agents in the skin.

Jul 1, 2021

Scientific paper
Product news

SARS-CoV-2 detection workflow in wastewater - Analytik Jena and project in Japan

In 2020 Analytik Jena real-time PCR thermal cyclers of the qTOWER³ series even supported one of the first SARS-CoV-2 wastewater screenings in Japan.

May 8, 2021

Scientific paper
Application

Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice

Radio-active sources have been used routinely for the preconditioning in humanized mouse models, but safety issues have motivated researchers to transition to chemical or X-ray based preconditioning. 

Dec 29, 2020

Scientific paper
Application
Product news

Elevated NSD3 histone methylation activity drives squamous cell lung cancer

This work identifies NSD3 as a principal 8p11-12 amplicon-associated oncogenic driver in LUSC, and suggests that NSD3-dependency renders LUSC therapeutically vulnerable to bromodomain inhibition.

Jun 8, 2021

Scientific paper
Application

Cytek Spectral cytometers : taking science one step further with 200+ Publications

Cytek Aurora is helping researchers around the world take their science further. See how in the 200+ publications in our resources center.

Apr 26, 2021

Scientific paper
Product news

Advances in Leukemia research using shear flow and Bioflux system

Leukemia is a rare cancer with many subtypes. The production of abnormal leukocytes create disruptions in the immune system and lead to a multitude of problems in the body.

Dec 10, 2020

Scientific paper
Application

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