Agilent provides xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.
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In vivo longitudinal 920 nm two-photon intravital kidney imaging of a dynamic 2,8-DHA crystal
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Revolutionize your Flow Cytometry and Sorting workflow with Cytek Biosciences
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Thermal Shift Assay using SYPRO Orange to Detect Protein Melting Temperatures
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A deep learning and Monte Carlo based framework for bioluminescence imaging center Maastro
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InAlyzer to evaluate G6PD activity in relation with frailty
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Flash news - did you know, that you can use Singulator S100 also for plant research?
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A novel real-time CTL assay to measure designer T-cell function against HIV Env(+) cells
Feb 19, 2018
Stimulated rhesus PBMCs with antibodies to CD3/CD28 and cotransduced T cells with CD4-CAR and maC46 vectors. CD4-CAR-transduced T cells were added to Env(+) 293T cells at E:T of 1:1. Killing of target cells was measured as reduced impedance. Has been observed gene expression in 60-70% of rhesus CD3(+) CD8(+) T cells with the individual vectors and in 35% of the cells with both vectors. CD4-CAR-transduced populations specifically killed Env(+) cells. In these studies, scientist showed that designer T cells were redirected to kill Env(+) cells. Control of viremia without HAART would revolutionize treatment for HIV patients.
Related technologies: Conventional flow cytometry
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