Agilent provides xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.
Automated microscopy and Spatial Proteomics
Automated microscopy and image analysis
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Study finds that automated liquid-handling operations are more robust, resilient, and efficient!
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Liquid handling devices (LHD) improve lab efficiency and accuracy. They automate liquid transfers, increase experiment...
Scaling Whole-Genome Sequencing to >50,000 single cells using cellenONE
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DNA Amplicon Library Preparation for Illumina® Sequencing
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X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization
Jun 5, 2024
Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...
Exosome-Mediated Delivery of Small Molecules, RNA & DNA for Development of Novel Cancer Therapeutics
Jun 3, 2024
Disha Moholkar of University of Louisville's Gupta Lab
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Emulate in vivo conditions – introduce shear flow to your experiments with BioFlux system
May 27, 2024
Most research is still conducted in vitro without the presence of flow. We use the BioFlux System to give you the...
High-frequency Ultrasound System For Preclinical Imaging
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Differentation displacement in acute myeloid leukemia through enhancer activation
Aug 7, 2018
LSD1 is a flavin adenine dinucleotide (FAD)-dependent homolog of the amine oxidase family and there was recently brought attention to it as a potential therapeutic target. The interest came from an observation of unusually high expression of LSD1 in certain types of poor-prognosis cancers. It was previously thought that LSD1 removes monomethyl and dymethyl histone marks. However, recently it was showed that it interacts with multiple transcripton factor. This raised a possibility of other drugs being used.
New inhibitor ORY-1001 was succesfully tested on LSD1 and blast cell differentioation was observed. The flow cytometric testing on this experiment was done with Novocyte. ORY-1001 disrupts the protein interaction between LSD1 and GFI1.
Related technologies: Conventional flow cytometry
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