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Real-time and quantitative analysis of Macrophage Phagocytosis with RTCA eSight

Agilent technologies

Feb 23, 2024

The eSight is currently the only instrument that interrogates cell health and behavior using cellular
impedance
...

Visualization of Tumor-Related Blood Vessels in Small Animals by Photoacoustic 3D Imaging System

Luxonus

Feb 21, 2024

In Vivo Label-Free Observation of Tumor-Related Blood Vessels in Small Animals Using a Newly Designed Photoacoustic 3D...

Therapeutic effects of mesenchymal stem cells in myocardial infarction

S-Sharp

Feb 19, 2024

Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem...

Whole-slide biomarker quantitation in 82-patient NSCLC cohort study of acquired resistance to PD-(L)

RareCyte

Feb 7, 2024

Samples from 82 patients with NSCLC and matched pre- and post-ICI biopsies were subjected to genomic profiling and to...

Evaluation with BLI of synthetic immune checkpoint engagers in allogenic mice

Spectral Instruments Imaging

Jan 17, 2024

Synthetic immune checkpoint engagers protect HLA-deficient iPSCs and derivatives from innate immune cell cytotoxicity

Application of focal X-ray irradiation in canaries

Precision X-Ray

Jan 15, 2024

Effects of the depletion of neural progenitors by focal X-ray irradiation on song production and perception in canaries

Radiation planning for image guided preclinical radiotherapy

Precision X-Ray

Jan 12, 2024

Doctoral Thesis, Stefan van Hoof, Maastricht University 2019

IVM and single cell transcriptomic analysis for engraftment of mesenchymal stem cells

IVIM Technology

Jan 10, 2024

To facilitate the translation of preclinical studies into clinical practice, the precise in vivo behaviors of the...

Small animal DXA instrument comparison and validation 2024

MEDIKORS

Jan 8, 2024

This study evaluated the performance of two relatively new peripheral bone densitometry machines, the InAlyzer and the...

Flexible multiplex panel design with new Orion Reagents

RareCyte

Jan 5, 2024

Orion Reagents are tailored to enable spatial biomarker quantitation rapidly, easily and with maximum flexibility....

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Single cell genotypic and phenotypic analysis of residual disease in acute myeloid leukemia

Nov 1, 2023

Understanding the biology enabling MRD clones to resist therapy is necessary to guide the development of more effective curative treatments. Discriminating between residual leukemic clones, preleukemic clones and normal precursors remains a challenge with current MRD tools. Herein, we developed a single cell (sc) MRD assay by combining flow cytometric enrichment of the targeted precursor/blast population with integrated scDNA sequencing and immunophenotyping. Our scMRD assay shows high sensitivity of approximately 0.01%, deconvolutes clonal architecture and provides clone-specific immunophenotypic data. In summary, our scMRD assay enhances MRD detection and simultaneously illuminates the clonal architecture of clonal hematopoiesis/pre-leukemic and leukemic cells surviving AML therapy.

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Mission Bio

Combining single-cell resolution with comprehensive biology from genotype to phenotype. Mission Bio is accelerating the discovery, development and delivery of precision medicine.

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The only single-cell multi-omics platform capable of simultaneously providing both genotype and phenotype data from the same cell, across thousands of cells.

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