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Webinar recording: Deep dive into Spatial Biology with MERSCOPE Ultra Platform
Aug 16, 2024
We invite you to learn more about MERSCOPE Ultra Platform. Webinar featuring Rob Mathis (Global Instrument Product...
Single-Cell Genomics applications ? Ideal work for the WOLF gentle cell sorter
Aug 2, 2024
The field of genomics and computational biology has progressed immensely over the last decade and new single-cell...
Study finds that automated liquid-handling operations are more robust, resilient, and efficient!
Jul 18, 2024
Liquid handling devices (LHD) improve lab efficiency and accuracy. They automate liquid transfers, increase experiment...
Scaling Whole-Genome Sequencing to >50,000 single cells using cellenONE
Jul 16, 2024
cellenONE technology enabled the creation of tens of thousands of high-quality single-cell genomes, paving the way for...
Theranostics: From Mice to Men and Back
Jun 25, 2024
Recorded webinar
Presenters: Prof. Dr. Ken Herrmann and Prof. Dr. Katharina Lückerath – Moderator: Hannah Notebaert
Orion 2024 AACR poster: 17-plex single-step stain and imaging of cell Lung Carcinoma
Jun 21, 2024
RareCyte Orion is a benchtop, high resolution, whole slide multimodal imaging instrument. A combination of quantitative...
Automated Purification of Viral DNA and RNA from Biological Samples usingZymo Research Quick-DNA/RNA
Jun 14, 2024
The Quick DNA/RNA Viral MagBead Kit from Zymo has been automated with the Cybio FeliX pipetting robot from Analytik...
DNA Amplicon Library Preparation for Illumina® Sequencing
Jun 12, 2024
The precision of temperature control, efficient heating and cooling rates, and excellent temperature homogeneity across...
X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization
Jun 5, 2024
Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...
Exosome-Mediated Delivery of Small Molecules, RNA & DNA for Development of Novel Cancer Therapeutics
Jun 3, 2024
Disha Moholkar of University of Louisville's Gupta Lab
Tuesday, June 11, 2024, 6:30 PM...
Nov 1, 2023
Understanding the biology enabling MRD clones to resist therapy is necessary to guide the development of more effective curative treatments. Discriminating between residual leukemic clones, preleukemic clones and normal precursors remains a challenge with current MRD tools. Herein, we developed a single cell (sc) MRD assay by combining flow cytometric enrichment of the targeted precursor/blast population with integrated scDNA sequencing and immunophenotyping. Our scMRD assay shows high sensitivity of approximately 0.01%, deconvolutes clonal architecture and provides clone-specific immunophenotypic data. In summary, our scMRD assay enhances MRD detection and simultaneously illuminates the clonal architecture of clonal hematopoiesis/pre-leukemic and leukemic cells surviving AML therapy.
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Combining single-cell resolution with comprehensive biology from genotype to phenotype. Mission Bio is accelerating the discovery, development and delivery of precision medicine.
More info at:
https://missionbio.com/
