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Webinar: Join us for an In-Depth Look at the Revolutionary Small Animal Radiotherapy System at STTARR

Precision X-Ray

Aug 17, 2023

Register for an engaging webinar led by Naz Chaudary, Ph.D., and Research Technician, Alex Wang from the...

Optimizing Gene Expression with Bioluminescence & the piggyBac System

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Aug 15, 2023

Discover how bioluminescence imaging & the piggyBac gene editing system optimize & track gene expression in mouse...

High-plex immunofluorescence imaging and traditional histology of the same tissue section

RareCyte

Aug 7, 2023

RareCyte Orion’ platform has been used for collecting H&E and high-plex immunofluorescence images from the same cells...

Single cell-resolution in situ sequencing elucidates spatial dynamics of multiple sclerosis

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MERFISH integrates spatial transcriptomics technology with high resolution spatial imaging, fluidics, image processing,...

MARS - High Efficiency Separation of CD34+ HSC from Mobilized Blood

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Jul 12, 2023

MARS platform provides an easy and cost-effective protocol for CD34+ cell isolation. Single pass CD34+ HSC enrichment...

43 markers, ONE tube : Impress yourself with Cytek Aurora Spectral Cytometer

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Using Cytek full spectrum flow cytometry, scientists at Hamad Medical Corporation, developed a 43 color panel to...

InAlyzer - The technology chosen by NASA

MEDIKORS

Jul 10, 2023

MEDIKORS's InAlyzer was finally selected as the equipment to be used for NASA's space environment biological research

Nature Article: The genomic landscape of pediatric acute lymphoblastic leukemia

Mission Bio

Jun 29, 2023

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Here, using whole-genome, exome and...

Brain-specific biomarkers in urine as a non-invasive approach to monitor neuronal and glial damage

Quanterix

Jun 28, 2023

This study evaluates the quantitative measurability of glial fibrillary acidic protein (GFAP), neurofilament light...

PET from Molecubes for imaging of neuroendocrine tumors

MOLECUBES

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Direct comparison of [18F]AlF-NOTA-JR11 and [18F]AlF-NOTA-octreotide for PET imaging of neuroendocrine tumors:...

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Cellular impedance measurement- novel method for in-vitro investigation of drug efficacy

Sep 12, 2017

Using standard cell lines, although attractive, can lead to unexpected results and probably to important differences when investigating a drug in primary cell lines isolated from patients. The opportunity to use cells of human origin may improve the predictive value of assays in drug testing and came hand in hand with the development of innovative real-time monitoring of cellular behaviour.

xCELLigence real time cell analyser offers a label-free non-invasive manner long-term recording of cellular signals. Considering all this aspects, the aim of our research was to evaluate the impedance of the primary melanocytes isolated from excised tumours that were confirmed as cutaneous melanoma. Primary cell cultures were used for establishing the efficacy pattern of a standard cytostatic, dacarbazine.
Our goal stands for obtaining a work flow for validating specific drug’s efficacy in individual tumour cells as a mean to personalize therapy in melanoma.

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Agilent technologies

Agilent provides xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.

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The RTCA DP Analyzer has three integrated stations for E-Plates 16 or CIM-Plates 16

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Located inside a tissue culture incubator, it is capable of switching any one of the wells on the E-Plate 96 to the RTCA Analyzer for impedance measurement

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Located inside a tissue culture incubator, it is capable of switching any one of the wells on any of six E-Plates to the RTCA Analyzer for impedance measurement

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Instrument can be integrated with automated liquid handling platforms or a robotic plate handler from different vendors

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