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Visualization of Tumor-Related Blood Vessels in Small Animals by Photoacoustic 3D Imaging System

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In Vivo Label-Free Observation of Tumor-Related Blood Vessels in Small Animals Using a Newly Designed Photoacoustic 3D...

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Samples from 82 patients with NSCLC and matched pre- and post-ICI biopsies were subjected to genomic profiling and to...

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Cytek is proud to announce the Cytek Orion reagent cocktail preparation system. The Cytek Orion system allows for...

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Radiation planning for image guided preclinical radiotherapy

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Doctoral Thesis, Stefan van Hoof, Maastricht University 2019

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Small animal DXA instrument comparison and validation 2024

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This study evaluated the performance of two relatively new peripheral bone densitometry machines, the InAlyzer and the...

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xCELLigence cancer immunotherapy: NK cell-mediated cytolysis

May 4, 2016

ACEA Biosciences developed a label-free assay format that allows dynamic monitoring of NK cell-mediated cytolysis. The assay uses impedancebased technology (RT-CES)4,5. This system is the predecessor of the new xCELLigence System. The attachment and interaction of adherent cells with wells on a 96X E-Plate leads to impedance changes, which correlate with cell number, size and shape. In contrast, addition of suspended cells to the wells results in undetectable changes due to non-existent or weak interaction with the electrodes. Therefore, NK cell-mediated cytolytic effects on the cancer cell monolayer can be quantitatively and dynamically monitored on the sensor plate without labeling the target cells.

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Agilent technologies

Agilent provides xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.

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The RTCA DP Analyzer has three integrated stations for E-Plates 16 or CIM-Plates 16

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Located inside a tissue culture incubator, it is capable of switching any one of the wells on the E-Plate 96 to the RTCA Analyzer for impedance measurement

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Located inside a tissue culture incubator, it is capable of switching any one of the wells on any of six E-Plates to the RTCA Analyzer for impedance measurement

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Instrument can be integrated with automated liquid handling platforms or a robotic plate handler from different vendors

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